Degradation of the sporopollenin exine capsules (SECs) in human plasma
The sporopollenin exine capsules (SECs) have recently attracted the attention of biological applications. The stability of SECs in human fluids is important issue to develop the controllable methods for the drug delivery system. Here, we analyzed the human plasma-triggered degradation of three speci...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/154653 |
| _version_ | 1811682253217988608 |
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| author | Fan, Teng-Fei Hwang, Youngkyu Potroz, Michael G. Lau, Kai-Lin Tan, Ee-Lin Mohammed Shahrudin Ibrahim Miyako, Eijiro Cho, Nam-Joon |
| author2 | School of Materials Science and Engineering |
| author_facet | School of Materials Science and Engineering Fan, Teng-Fei Hwang, Youngkyu Potroz, Michael G. Lau, Kai-Lin Tan, Ee-Lin Mohammed Shahrudin Ibrahim Miyako, Eijiro Cho, Nam-Joon |
| author_sort | Fan, Teng-Fei |
| collection | NTU |
| description | The sporopollenin exine capsules (SECs) have recently attracted the attention of biological applications. The stability of SECs in human fluids is important issue to develop the controllable methods for the drug delivery system. Here, we analyzed the human plasma-triggered degradation of three species of SECs, i.e., camellia (Camellia sinensis L.), cattail (Typha angustifolia L.), and dandelion (Taraxacum officinale L.), regarding the physical and chemical aspects. The field emission scanning electron microscopy (FESEM) images showed no significant changes in the surface morphology of the SECs as increasing incubation time in human plasma, but we observed the increase of the rupture ratio by dynamic image particle analysis (DIPA). Also, Fourier-transform infrared spectroscopy (FTIR) combined with principal component analysis (PCA) addressed the chemical degradation in a species-specific manner. Specifically, the O[sbnd]H groups of camellia SECs, C[sbnd]O[sbnd]C groups of cattail SECs, and C[dbnd]O groups of dandelion SECs showed significant changes. |
| first_indexed | 2024-10-01T03:53:54Z |
| format | Journal Article |
| id | ntu-10356/154653 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:53:54Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | ntu-10356/1546532021-12-30T07:12:24Z Degradation of the sporopollenin exine capsules (SECs) in human plasma Fan, Teng-Fei Hwang, Youngkyu Potroz, Michael G. Lau, Kai-Lin Tan, Ee-Lin Mohammed Shahrudin Ibrahim Miyako, Eijiro Cho, Nam-Joon School of Materials Science and Engineering Engineering::Materials Pollen Sporopollenin Exine Capsules The sporopollenin exine capsules (SECs) have recently attracted the attention of biological applications. The stability of SECs in human fluids is important issue to develop the controllable methods for the drug delivery system. Here, we analyzed the human plasma-triggered degradation of three species of SECs, i.e., camellia (Camellia sinensis L.), cattail (Typha angustifolia L.), and dandelion (Taraxacum officinale L.), regarding the physical and chemical aspects. The field emission scanning electron microscopy (FESEM) images showed no significant changes in the surface morphology of the SECs as increasing incubation time in human plasma, but we observed the increase of the rupture ratio by dynamic image particle analysis (DIPA). Also, Fourier-transform infrared spectroscopy (FTIR) combined with principal component analysis (PCA) addressed the chemical degradation in a species-specific manner. Specifically, the O[sbnd]H groups of camellia SECs, C[sbnd]O[sbnd]C groups of cattail SECs, and C[dbnd]O groups of dandelion SECs showed significant changes. Nanyang Technological University National Research Foundation (NRF) This work was supported by the Competitive Research Programme (NRF-CRP10-2012-07) at the National Research Foundation of Singapore (NRF) and by the Creative Materials Discovery Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning (2016M3D1A1024098). The research also benefited from aid from a Start-Up Grant (SUG) from the Nanyang Technological University (M4080751.070). Also, this work was also supported by a Japan Society for the Promotion of Science (JSPS) KAKENHI Grant-in-Aid for Scientific Research (B) (no. 16H03834) and the JSPS KAKENHI Fund for the Promotion of Joint International Research (Fostering Joint International Research) (no. 16KK0117). 2021-12-30T07:12:24Z 2021-12-30T07:12:24Z 2020 Journal Article Fan, T., Hwang, Y., Potroz, M. G., Lau, K., Tan, E., Mohammed Shahrudin Ibrahim, Miyako, E. & Cho, N. (2020). Degradation of the sporopollenin exine capsules (SECs) in human plasma. Applied Materials Today, 19, 100594-. https://dx.doi.org/10.1016/j.apmt.2020.100594 2352-9407 https://hdl.handle.net/10356/154653 10.1016/j.apmt.2020.100594 2-s2.0-85079094530 19 100594 en NRF-CRP10-2012-07 M4080751.070 Applied Materials Today © 2020 Elsevier Ltd. All rights reserved. |
| spellingShingle | Engineering::Materials Pollen Sporopollenin Exine Capsules Fan, Teng-Fei Hwang, Youngkyu Potroz, Michael G. Lau, Kai-Lin Tan, Ee-Lin Mohammed Shahrudin Ibrahim Miyako, Eijiro Cho, Nam-Joon Degradation of the sporopollenin exine capsules (SECs) in human plasma |
| title | Degradation of the sporopollenin exine capsules (SECs) in human plasma |
| title_full | Degradation of the sporopollenin exine capsules (SECs) in human plasma |
| title_fullStr | Degradation of the sporopollenin exine capsules (SECs) in human plasma |
| title_full_unstemmed | Degradation of the sporopollenin exine capsules (SECs) in human plasma |
| title_short | Degradation of the sporopollenin exine capsules (SECs) in human plasma |
| title_sort | degradation of the sporopollenin exine capsules secs in human plasma |
| topic | Engineering::Materials Pollen Sporopollenin Exine Capsules |
| url | https://hdl.handle.net/10356/154653 |
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