Biaryl cross-coupling enabled by photo-induced electron transfer

Biaryl cross-coupling enabled by photo-induced electron transfer

We report a protocol for aryl cross-coupling of electron-deficient aryl halides with electron-rich (hetero)arenes that is driven solely by violet light. This process takes advantage of formation of photo-excited state of electron-deficient aryl halides, that are reduced by electron-rich (hetero)aren...

Full description

Bibliographic Details
Main Authors: Hayashi, Hirohito, Wang, Bin, Wu, Xiangyang, Teo, Shi Jie, Kaga, Atsushi, Watanabe, Kohei, Takita, Ryo, Yeow, Edwin Kok Lee, Chiba, Shunsuke
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
Aryl Radicals
Anion Radicals
Online Access:https://hdl.handle.net/10356/154836
Description
Summary:We report a protocol for aryl cross-coupling of electron-deficient aryl halides with electron-rich (hetero)arenes that is driven solely by violet light. This process takes advantage of formation of photo-excited state of electron-deficient aryl halides, that are reduced by electron-rich (hetero)arenes to form a pair of aryl anion and cation radicals. The resulting aryl anion radicals of aryl halides undergo mesolysis of the carbon-halogen bond to generate aryl radicals, that are coupled most likely with aryl cation radicals to afford functionalized biaryls. (Figure presented.).

Similar Items