Synthesis of fasicularin
The synthesis of a tricyclic marine alkaloid, fasicularin, was accomplished. Stereoselective synthesis of the aza-spirocyclic BC-ring precursor and ensuing construction of the A-ring with stereocontrolled installation of the C2 hexyl group feature prominently in the synthesis.
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2022
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| Online Access: | https://hdl.handle.net/10356/154863 |
| _version_ | 1826130055609188352 |
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| author | Kaga, Atsushi Tnay, Ya Lin Chiba, Shunsuke |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Kaga, Atsushi Tnay, Ya Lin Chiba, Shunsuke |
| author_sort | Kaga, Atsushi |
| collection | NTU |
| description | The synthesis of a tricyclic marine alkaloid, fasicularin, was accomplished. Stereoselective synthesis of the aza-spirocyclic BC-ring precursor and ensuing construction of the A-ring with stereocontrolled installation of the C2 hexyl group feature prominently in the synthesis. |
| first_indexed | 2024-10-01T07:50:18Z |
| format | Journal Article |
| id | ntu-10356/154863 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:50:18Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | ntu-10356/1548632023-02-28T19:59:10Z Synthesis of fasicularin Kaga, Atsushi Tnay, Ya Lin Chiba, Shunsuke School of Physical and Mathematical Sciences Science::Chemistry Transfer Reactions Aziridines The synthesis of a tricyclic marine alkaloid, fasicularin, was accomplished. Stereoselective synthesis of the aza-spirocyclic BC-ring precursor and ensuing construction of the A-ring with stereocontrolled installation of the C2 hexyl group feature prominently in the synthesis. Ministry of Education (MOE) Nanyang Technological University Accepted version This work was supported by funding from Nanyang Technological University and the Singapore Ministry of Education and Singapore Ministry of Education (Academic Research Fund Tier 1: RG4/13). 2022-01-17T02:31:35Z 2022-01-17T02:31:35Z 2016 Journal Article Kaga, A., Tnay, Y. L. & Chiba, S. (2016). Synthesis of fasicularin. Organic Letters, 18(14), 3506-3508. https://dx.doi.org/10.1021/acs.orglett.6b01669 1523-7060 https://hdl.handle.net/10356/154863 10.1021/acs.orglett.6b01669 27355342 2-s2.0-84978695883 14 18 3506 3508 en RG4/13 Organic Letters This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.6b01669. application/pdf |
| spellingShingle | Science::Chemistry Transfer Reactions Aziridines Kaga, Atsushi Tnay, Ya Lin Chiba, Shunsuke Synthesis of fasicularin |
| title | Synthesis of fasicularin |
| title_full | Synthesis of fasicularin |
| title_fullStr | Synthesis of fasicularin |
| title_full_unstemmed | Synthesis of fasicularin |
| title_short | Synthesis of fasicularin |
| title_sort | synthesis of fasicularin |
| topic | Science::Chemistry Transfer Reactions Aziridines |
| url | https://hdl.handle.net/10356/154863 |
| work_keys_str_mv | AT kagaatsushi synthesisoffasicularin AT tnayyalin synthesisoffasicularin AT chibashunsuke synthesisoffasicularin |