Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2

COVID-19 is a respiratory illness caused by a novel coronavirus called SARS-CoV-2. The viral spike (S) protein engages the human angiotensin-converting enzyme 2 (ACE2) receptor to invade host cells with ~10-15-fold higher affinity compared to SARS-CoV S-protein, making it highly infectious. Here, we...

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Bibliographic Details
Main Authors: Suryamohan, Kushal, Diwanji, Devan, Stawiski, Eric W., Gupta, Ravi, Miersch, Shane, Liu, Jiang, Chen, Chao, Jiang, Ying-Ping, Fellouse, Frederic A., Sathirapongsasuti, J. Fah, Albers, Patrick K., Deepak, Tanneeru, Saberianfar, Reza, Ratan, Aakrosh, Washburn, Gavin, Mis, Monika, Santhosh, Devi, Somasekar, Sneha, Hiranjith, G. H., Vargas, Derek, Mohan, Sangeetha, Phalke, Sameer, Kuriakose, Boney, Antony, Aju, Ustav, Mart, Schuster, Stephan Christoph, Sidhu, Sachdev, Junutula, Jagath R., Jura, Natalia, Seshagiri, Somasekar
Other Authors: Singapore Centre for Environmental Life Sciences and Engineering
Format: Journal Article
Language:English
Published: 2022
Subjects:
Engineering::Environmental engineering
Spike Protein
Structural-Analysis
Online Access:https://hdl.handle.net/10356/154952

Internet

https://hdl.handle.net/10356/154952

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