Carbene-catalyzed enantioselective hydrophosphination of α-bromoenals to prepare phosphine-containing chiral molecules

Carbene-catalyzed enantioselective hydrophosphination of α-bromoenals to prepare phosphine-containing chiral molecules

Disclosed herein is the first carbene-organocatalyzed asymmetric addition of phosphine nucleophiles to the in situ generated α,β-unsaturated acyl azolium intermediates. Our reaction enantioselectively constructs carbon-phosphine bonds and prepares chiral phosphines with high optical purities. The ph...

Full description

Bibliographic Details
Main Authors: Maiti, Rakesh, Yan, Jia-Lei, Yang, Xing, Mondal, Bivas, Xu, Jun, Chai, Huifang, Jin, Zhichao, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
Asymmetric Hydrophosphination
Chiral Phosphine
Online Access:https://hdl.handle.net/10356/155058

Similar Items

Similar Items