Carbene-catalyzed enantioselective annulation of dinucleophilic hydrazones and bromoenals for access to aryl-dihydropyridazinones and related drugs
4,5-Dihydropyridazinones bearing an aryl substituent at the C6-position are important motifs in drug molecules. Herein, we developed an efficient protocol to access aryl-dihydropyridazinone molecules via carbene-catalyzed asymmetric annulation between dinucleophilic arylidene hydrazones and bromoena...
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Bibliographic Details
Main Authors: |
Mondal, Bivas,
Maiti, Rakesh,
Yang, Xing,
Xu, Jun,
Tian, Weiyi,
Yan, Jia-Lei,
Li, Xiangyang,
Chi, Robin Yonggui |
Other Authors: |
School of Physical and Mathematical Sciences |
Format: | Journal Article
|
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/155061
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