Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes
Palladium-catalyzed three-component carboetherification of cyclic alkenes proceeded to give trans adducts exclusively with excellent enantioselectivity through a Wacker-type pathway. The reaction is also applicable to other oxygen nucleophiles, such as water, phenols, and carboxylic acids, as well a...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Language: | English |
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2022
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| Online Access: | https://hdl.handle.net/10356/155085 |
| _version_ | 1811681271912333312 |
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| author | Teng, Shenghan Jiao, Zhiwei Chi, Robin Yonggui Zhou, Steve Jianrong |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Teng, Shenghan Jiao, Zhiwei Chi, Robin Yonggui Zhou, Steve Jianrong |
| author_sort | Teng, Shenghan |
| collection | NTU |
| description | Palladium-catalyzed three-component carboetherification of cyclic alkenes proceeded to give trans adducts exclusively with excellent enantioselectivity through a Wacker-type pathway. The reaction is also applicable to other oxygen nucleophiles, such as water, phenols, and carboxylic acids, as well as some electron-poor aryl amines. |
| first_indexed | 2024-10-01T03:38:18Z |
| format | Journal Article |
| id | ntu-10356/155085 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:38:18Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | ntu-10356/1550852023-02-28T19:52:23Z Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes Teng, Shenghan Jiao, Zhiwei Chi, Robin Yonggui Zhou, Steve Jianrong School of Physical and Mathematical Sciences Science::Chemistry Allenes Asymmetric Catalysis Palladium-catalyzed three-component carboetherification of cyclic alkenes proceeded to give trans adducts exclusively with excellent enantioselectivity through a Wacker-type pathway. The reaction is also applicable to other oxygen nucleophiles, such as water, phenols, and carboxylic acids, as well as some electron-poor aryl amines. Agency for Science, Technology and Research (A*STAR) Economic Development Board (EDB) Accepted version We acknowledge financial support from Peking University Shenzhen Graduate School, Shenzhen Bay Laboratory (21230011-Scripps), Nanyang Technological University, the GSK-EDB Trust Fund (2017 GSK-EDB Green and Sustainable Manufacturing Award), and A*STAR Science and Engineering Research Council (AMEIRGA1783c0010).. 2022-02-08T08:48:03Z 2022-02-08T08:48:03Z 2020 Journal Article Teng, S., Jiao, Z., Chi, R. Y. & Zhou, S. J. (2020). Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes. Angewandte Chemie International Edition, 59(6), 2246-2250. https://dx.doi.org/10.1002/anie.201911961 1433-7851 https://hdl.handle.net/10356/155085 10.1002/anie.201911961 31691440 2-s2.0-85077078795 6 59 2246 2250 en AME IRG A1783c0010 Angewandte Chemie International Edition This is the peer reviewed version of the following article: Teng, S., Jiao, Z., Chi, R. Y. & Zhou, S. J. (2020). Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes. Angewandte Chemie International Edition, 59(6), 2246-2250, which has been published in final form at https://doi.org/10.1002/anie.201911961. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. application/pdf |
| spellingShingle | Science::Chemistry Allenes Asymmetric Catalysis Teng, Shenghan Jiao, Zhiwei Chi, Robin Yonggui Zhou, Steve Jianrong Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes |
| title | Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes |
| title_full | Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes |
| title_fullStr | Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes |
| title_full_unstemmed | Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes |
| title_short | Asymmetric Wacker-type oxyallenylation and azaallenylation of cyclic alkenes |
| title_sort | asymmetric wacker type oxyallenylation and azaallenylation of cyclic alkenes |
| topic | Science::Chemistry Allenes Asymmetric Catalysis |
| url | https://hdl.handle.net/10356/155085 |
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