Asymmetric reductive and alkynylative heck bicyclization of enynes to access conformationally restricted aza[3.1.0]bicycles

Asymmetric reductive and alkynylative heck bicyclization of enynes to access conformationally restricted aza[3.1.0]bicycles

Conformationally restricted azabicycles are becoming increasingly important in medicinal research. Asymmetric Heck bicyclization of enynes proceeds to give medicinally useful aza[3.1.0] and aza[4.1.0] bicycles with excellent enantioselectivity. The key organopalladium species after bicyclization can...

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Bibliographic Details
Main Authors: Huang, Xiaolei, Nguyen, Minh Hieu, Pu, Maoping, Zhang, Luoqiang, Chi, Robin Yonggui, Wu, Yun-Dong, Zhou, Steve Jianrong
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
Alkynylation
Azabicycles
Online Access:https://hdl.handle.net/10356/155086

Internet

https://hdl.handle.net/10356/155086

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