Mutational analysis of mycobacterial F‑ATP synthase subunit δ leads to a potent δ enzyme inhibitor

Mutational analysis of mycobacterial F‑ATP synthase subunit δ leads to a potent δ enzyme inhibitor

While many bacteria are able to bypass the requirement for oxidative phosphorylation when grown on carbohydrates, Mycobacterium tuberculosis is unable to do so. Differences of amino acid composition and structural features of the mycobacterial F-ATP synthase (α3:β3:γ:δ:ε:a:b:b′:c9) compared to its p...

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Bibliographic Details
Main Authors:	Harikishore, Amaravadhi, Saw, Wuan-Geok, Ragunathan, Priya, Litty, Dennnis, Dick, Thomas, Müller, Volker, Grüber, Gerhard
Other Authors:	School of Biological Sciences
Format:	Journal Article
Language:	English
Published:	2022
Subjects:	Science::Biological sciences::Biochemistry Tuberculosis Mycobacteria
Online Access:	https://hdl.handle.net/10356/155759

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