Temperature effects on the phase behaviour of PMPC polymer

Poly(2-methacryloxyehtyl phosphorylcholine) (PMPC) shows great potential in the biomedical industry. This is due to their high biocompatibility and bio-inertness. They also possess properties such as anti-fouling and lubricative. Due to all these properties, it can be utilise as coating for implants...

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Main Author: Woo, Kok Jian
Other Authors: Yu Jing
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/156211
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author Woo, Kok Jian
author2 Yu Jing
author_facet Yu Jing
Woo, Kok Jian
author_sort Woo, Kok Jian
collection NTU
description Poly(2-methacryloxyehtyl phosphorylcholine) (PMPC) shows great potential in the biomedical industry. This is due to their high biocompatibility and bio-inertness. They also possess properties such as anti-fouling and lubricative. Due to all these properties, it can be utilise as coating for implants to reduce osteolysis. PMPC, however, has not been well studied in terms of its phase behaviour. To do that, the aim of this project is to analyse the phase behaviour of PMPC polymer and hence construct a phase diagram. UV-Vis spectrometry is used to analyse the phase behavior of the polymer. To determine the phase transition temperature, data obtained from the spectrometry are used to plot against the polymer concentration. Then only phase diagram can be determined. The phase diagram constructed shows that PMPC exhibit combination of Upper Critical Solution Temperature (UCST) and Lower Critical Solution Temperature (LCST), and a single-phase in between the UCST and LCST. Furthermore, UCST and LCST both showed a decreasing trend when concentration of polymer increases.
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spelling ntu-10356/1562112022-04-07T02:48:41Z Temperature effects on the phase behaviour of PMPC polymer Woo, Kok Jian Yu Jing School of Materials Science and Engineering yujing@ntu.edu.sg Engineering::Materials Poly(2-methacryloxyehtyl phosphorylcholine) (PMPC) shows great potential in the biomedical industry. This is due to their high biocompatibility and bio-inertness. They also possess properties such as anti-fouling and lubricative. Due to all these properties, it can be utilise as coating for implants to reduce osteolysis. PMPC, however, has not been well studied in terms of its phase behaviour. To do that, the aim of this project is to analyse the phase behaviour of PMPC polymer and hence construct a phase diagram. UV-Vis spectrometry is used to analyse the phase behavior of the polymer. To determine the phase transition temperature, data obtained from the spectrometry are used to plot against the polymer concentration. Then only phase diagram can be determined. The phase diagram constructed shows that PMPC exhibit combination of Upper Critical Solution Temperature (UCST) and Lower Critical Solution Temperature (LCST), and a single-phase in between the UCST and LCST. Furthermore, UCST and LCST both showed a decreasing trend when concentration of polymer increases. Bachelor of Engineering (Materials Engineering) 2022-04-07T02:48:41Z 2022-04-07T02:48:41Z 2022 Final Year Project (FYP) Woo, K. J. (2022). Temperature effects on the phase behaviour of PMPC polymer. Final Year Project (FYP), Nanyang Technological University, Singapore. https://hdl.handle.net/10356/156211 https://hdl.handle.net/10356/156211 en application/pdf Nanyang Technological University
spellingShingle Engineering::Materials
Woo, Kok Jian
Temperature effects on the phase behaviour of PMPC polymer
title Temperature effects on the phase behaviour of PMPC polymer
title_full Temperature effects on the phase behaviour of PMPC polymer
title_fullStr Temperature effects on the phase behaviour of PMPC polymer
title_full_unstemmed Temperature effects on the phase behaviour of PMPC polymer
title_short Temperature effects on the phase behaviour of PMPC polymer
title_sort temperature effects on the phase behaviour of pmpc polymer
topic Engineering::Materials
url https://hdl.handle.net/10356/156211
work_keys_str_mv AT wookokjian temperatureeffectsonthephasebehaviourofpmpcpolymer