Role of lipid droplets and FITM2 in beta-cell physiology and pathophysiology
Hyperlipidemia is a known driving factor of T2DM, with saturated fatty acids (SFAs) pinpointed as the causation of β cell failure. Hence, intracellular handling of these SFAs, in β cells, was thought to be vital in preventing the loss of its function. The biogenesis of lipid droplets (LDs) forms an...
Main Author: | Ho, Calvin Qing Wei |
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Other Authors: | Yusuf Ali |
Format: | Thesis-Doctor of Philosophy |
Language: | English |
Published: |
Nanyang Technological University
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/158047 |
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