The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering
Plastic pollution in diverse terrestrial and marine environments is a widely recognised and growing problem. Bio-recycling and upcycling of plastic waste is a potential solution to plastic pollution, as these processes convert plastic waste into useful materials. Polyethylene terephthalate (PET) is...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2022
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| Online Access: | https://hdl.handle.net/10356/158715 |
| _version_ | 1811685747638403072 |
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| author | Pasula, Rupali Reddy Lim, Sierin Ghadessy, Farid J. Sana, Barindra |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Pasula, Rupali Reddy Lim, Sierin Ghadessy, Farid J. Sana, Barindra |
| author_sort | Pasula, Rupali Reddy |
| collection | NTU |
| description | Plastic pollution in diverse terrestrial and marine environments is a widely recognised and growing problem. Bio-recycling and upcycling of plastic waste is a potential solution to plastic pollution, as these processes convert plastic waste into useful materials. Polyethylene terephthalate (PET) is the most abundant plastic waste, and this material can be degraded by a class of recently discovered bacterial esterase enzymes known as PET hydrolases (PETase). Investigations of the enzymatic hydrolysis of diverse PET molecules have clearly revealed that the biodegradability of various PET substrates depends on both their chemical structure and physical properties, including polymer length, crystallinity, glass transition temperature, surface area, and surface charge. This review summarises the known impacts of crystallinity and other physical properties on enzymatic PET hydrolysis. |
| first_indexed | 2024-10-01T04:49:26Z |
| format | Journal Article |
| id | ntu-10356/158715 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:49:26Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | ntu-10356/1587152023-12-29T06:48:16Z The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering Pasula, Rupali Reddy Lim, Sierin Ghadessy, Farid J. Sana, Barindra School of Chemical and Biomedical Engineering Engineering::Bioengineering PET Degradation PET Hydrolase Enzyme Engineering Plastic pollution in diverse terrestrial and marine environments is a widely recognised and growing problem. Bio-recycling and upcycling of plastic waste is a potential solution to plastic pollution, as these processes convert plastic waste into useful materials. Polyethylene terephthalate (PET) is the most abundant plastic waste, and this material can be degraded by a class of recently discovered bacterial esterase enzymes known as PET hydrolases (PETase). Investigations of the enzymatic hydrolysis of diverse PET molecules have clearly revealed that the biodegradability of various PET substrates depends on both their chemical structure and physical properties, including polymer length, crystallinity, glass transition temperature, surface area, and surface charge. This review summarises the known impacts of crystallinity and other physical properties on enzymatic PET hydrolysis. National Research Foundation (NRF) Published version This publication is supported by the National Research Foundation, Singapore, under its Competitive Research Programme (Award# NRF-CRP22-2019-0005) 2022-05-23T08:45:41Z 2022-05-23T08:45:41Z 2022 Journal Article Pasula, R. R., Lim, S., Ghadessy, F. J. & Sana, B. (2022). The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering. Engineering Biology, 6(1), 17-22. https://dx.doi.org/10.1049/enb2.12018 2398-6182 https://hdl.handle.net/10356/158715 10.1049/enb2.12018 1 6 17 22 en NRF-CRP22-2019-0005 Engineering Biology © 2022 The Authors. Engineering Biology published by John Wiley & Sons Ltd on behalf of The Institution of Engineering and Technology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. application/pdf |
| spellingShingle | Engineering::Bioengineering PET Degradation PET Hydrolase Enzyme Engineering Pasula, Rupali Reddy Lim, Sierin Ghadessy, Farid J. Sana, Barindra The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering |
| title | The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering |
| title_full | The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering |
| title_fullStr | The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering |
| title_full_unstemmed | The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering |
| title_short | The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering |
| title_sort | influences of substrates physical properties on enzymatic pet hydrolysis implications for pet hydrolase engineering |
| topic | Engineering::Bioengineering PET Degradation PET Hydrolase Enzyme Engineering |
| url | https://hdl.handle.net/10356/158715 |
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