Machine learning applications on biological data

Machine learning has been used frequently for biological studies with applications of prediction, discovery and classification. With the flux of multiple types of largescale data, the development of machine learning methods, especially the application of deep learning approaches, has become more...

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Main Author: Xu, Ying
Other Authors: Lin Weisi
Format: Thesis-Master by Research
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/159232
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author Xu, Ying
author2 Lin Weisi
author_facet Lin Weisi
Xu, Ying
author_sort Xu, Ying
collection NTU
description Machine learning has been used frequently for biological studies with applications of prediction, discovery and classification. With the flux of multiple types of largescale data, the development of machine learning methods, especially the application of deep learning approaches, has become more promising. This thesis studies machine learning applications on ageing research as a stochastic model. We review the exploration of relationships between certain types of DNA repair and ageing, the function of age-related proteins in molecular pathways and relationships between ageing and apoptosis. The research shows how machine learning algorithms can be further improved coupled with state-of-the-art molecular analysis technologies. Furthermore, we build a deep neural network for plant video classification for a typical application of pesticide spraying drone. Plants can act differently under different growth stage, soil fertility, availability of water, climate, diseases or pests. Video classification of plants according to the waving feature is important for the pilotless aerial vehicles to spray pesticides selectively and improve automation of precision agriculture.
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spelling ntu-10356/1592322022-06-20T07:47:13Z Machine learning applications on biological data Xu, Ying Lin Weisi School of Computer Science and Engineering WSLin@ntu.edu.sg Engineering::Computer science and engineering Engineering::Bioengineering Machine learning has been used frequently for biological studies with applications of prediction, discovery and classification. With the flux of multiple types of largescale data, the development of machine learning methods, especially the application of deep learning approaches, has become more promising. This thesis studies machine learning applications on ageing research as a stochastic model. We review the exploration of relationships between certain types of DNA repair and ageing, the function of age-related proteins in molecular pathways and relationships between ageing and apoptosis. The research shows how machine learning algorithms can be further improved coupled with state-of-the-art molecular analysis technologies. Furthermore, we build a deep neural network for plant video classification for a typical application of pesticide spraying drone. Plants can act differently under different growth stage, soil fertility, availability of water, climate, diseases or pests. Video classification of plants according to the waving feature is important for the pilotless aerial vehicles to spray pesticides selectively and improve automation of precision agriculture. Master of Engineering 2022-06-20T07:47:13Z 2022-06-20T07:47:13Z 2022 Thesis-Master by Research Xu, Y. (2022). Machine learning applications on biological data. Master's thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/159232 https://hdl.handle.net/10356/159232 en This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). application/pdf Nanyang Technological University
spellingShingle Engineering::Computer science and engineering
Engineering::Bioengineering
Xu, Ying
Machine learning applications on biological data
title Machine learning applications on biological data
title_full Machine learning applications on biological data
title_fullStr Machine learning applications on biological data
title_full_unstemmed Machine learning applications on biological data
title_short Machine learning applications on biological data
title_sort machine learning applications on biological data
topic Engineering::Computer science and engineering
Engineering::Bioengineering
url https://hdl.handle.net/10356/159232
work_keys_str_mv AT xuying machinelearningapplicationsonbiologicaldata