Contributions to the studies of asparaginyl peptide ligases and to the design of inhibitors targeting bacterial tRNA methyltransferases
Enzymes constitute very important macromolecular catalysts with a wide range of biological activities. During my thesis work, I have studied two important enzymes using a combination of biochemical and structural biology tools. So my thesis is naturally broken down into two main parts, each part bei...
Main Author: | Wong, Yee Hwa |
---|---|
Other Authors: | Julien Lescar |
Format: | Thesis-Doctor of Philosophy |
Language: | English |
Published: |
Nanyang Technological University
2022
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/159270 |
Similar Items
Similar Items
-
Targeting the bacterial epitranscriptome for antibiotic development : discovery of novel tRNA-(N1G37) methyltransferase (TrmD) inhibitors
by: Zhong, Wenhe, et al.
Published: (2021) -
Structural and functional studies of peptide asparaginyl ligases
by: Hu, Side
Published: (2022) -
Expanding the substrate specificity of peptide asparaginyl ligase
by: Chua, Niying
Published: (2023) -
Protein engineering using asparaginyl peptide ligases
by: Wang, Zhen
Published: (2023) -
Expanding the scope of substrate specificity for peptide asparaginyl ligases
by: Lim, Ching Koon
Published: (2023)