Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives
There is a growing interest in developing innovative adhesive materials that offer stimuli-responsive mechanical properties. Electrocuring adhesives exploit electric-field stimuli towards initiating and propagating polymerization reactions with projected benefits of on-demand adhesion and microelect...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/159909 |
| _version_ | 1811695580676620288 |
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| author | Ambrosi, Adriano Singh, Manisha Webster, Richard David Steele, Terry W. J. |
| author2 | School of Materials Science and Engineering |
| author_facet | School of Materials Science and Engineering Ambrosi, Adriano Singh, Manisha Webster, Richard David Steele, Terry W. J. |
| author_sort | Ambrosi, Adriano |
| collection | NTU |
| description | There is a growing interest in developing innovative adhesive materials that offer stimuli-responsive mechanical properties. Electrocuring adhesives exploit electric-field stimuli towards initiating and propagating polymerization reactions with projected benefits of on-demand adhesion and microelectronic control. Voltaglue is a recently developed biocompatible, water-based bioadhesive that combines a biomacromolecule (polyamidoamine, PAMAM) with a grafted electrochemical crosslinker (diazirine) where the former mediates viscoelastic properties and the latter voltage-based activation. Through this relatively simple design, a range of viscoelastic and adhesive properties are possible by controlling the intensity (voltage) and duration (coulombs) of the electric field. For the first time, bioadhesive properties are correlated to the moles of diazirine reduced during electrocuring via chronoamperograms. The method is based on the precise measurement of the charge exchanged during the reductive reaction which ultimately results in a series of voltage/time combinations that can be used to drive diazirine activation and charge quantitation. A strong correlation is finally observed between diazirine electrolysis and specific mechanical properties of the cured adhesive. This ultimately enables fine-tune control over the adhesive properties with benefits in a wide variety of applications ranging from electromagnetic biomaterials to additive manufacturing. |
| first_indexed | 2024-10-01T07:25:44Z |
| format | Journal Article |
| id | ntu-10356/159909 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:25:44Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | ntu-10356/1599092022-07-12T00:44:15Z Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives Ambrosi, Adriano Singh, Manisha Webster, Richard David Steele, Terry W. J. School of Materials Science and Engineering Interdisciplinary Graduate School (IGS) School of Physical and Mathematical Sciences Ministry of Education NTU-Northwestern Institute for Nanomedicine Science::Chemistry Bioadhesive Diazirine There is a growing interest in developing innovative adhesive materials that offer stimuli-responsive mechanical properties. Electrocuring adhesives exploit electric-field stimuli towards initiating and propagating polymerization reactions with projected benefits of on-demand adhesion and microelectronic control. Voltaglue is a recently developed biocompatible, water-based bioadhesive that combines a biomacromolecule (polyamidoamine, PAMAM) with a grafted electrochemical crosslinker (diazirine) where the former mediates viscoelastic properties and the latter voltage-based activation. Through this relatively simple design, a range of viscoelastic and adhesive properties are possible by controlling the intensity (voltage) and duration (coulombs) of the electric field. For the first time, bioadhesive properties are correlated to the moles of diazirine reduced during electrocuring via chronoamperograms. The method is based on the precise measurement of the charge exchanged during the reductive reaction which ultimately results in a series of voltage/time combinations that can be used to drive diazirine activation and charge quantitation. A strong correlation is finally observed between diazirine electrolysis and specific mechanical properties of the cured adhesive. This ultimately enables fine-tune control over the adhesive properties with benefits in a wide variety of applications ranging from electromagnetic biomaterials to additive manufacturing. Agency for Science, Technology and Research (A*STAR) Nanyang Technological University A.A. acknowledges the support of the Double-Hundred Program for Foreign Experts of Shandong Province (WST2019011). T.W.J.S. acknowledges the generous support of NTU-Northwestern Institute for Nanomedicine Grant: 3D-Printing of Electro-Curing Nano-composite Living Electrodes for Cardiac Tissue Regeneration; Agency for Science, Technology and Research (A*Star) IRG17283008 ‘Microprocessor-based methods of composite curing’. 2022-07-05T07:26:34Z 2022-07-05T07:26:34Z 2021 Journal Article Ambrosi, A., Singh, M., Webster, R. D. & Steele, T. W. J. (2021). Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives. ChemElectroChem, 8(14), 2715-2725. https://dx.doi.org/10.1002/celc.202100594 2196-0216 https://hdl.handle.net/10356/159909 10.1002/celc.202100594 2-s2.0-85111666924 14 8 2715 2725 en IRG17283008 ChemElectroChem © 2021 Wiley-VCHGmbH. All rights reserved. |
| spellingShingle | Science::Chemistry Bioadhesive Diazirine Ambrosi, Adriano Singh, Manisha Webster, Richard David Steele, Terry W. J. Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives |
| title | Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives |
| title_full | Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives |
| title_fullStr | Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives |
| title_full_unstemmed | Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives |
| title_short | Precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives |
| title_sort | precise control of diazirine reduction to tune the mechanical properties of electrocuring adhesives |
| topic | Science::Chemistry Bioadhesive Diazirine |
| url | https://hdl.handle.net/10356/159909 |
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