Can glycosylation mask the detection of MHC expressing p53 peptides by T cell receptors?
Proteins of the major histocompatibility complex (MHC) class I, or human leukocyte antigen (HLA) in humans interact with endogenous peptides and present them to T cell receptors (TCR), which in turn tune the immune system to recognize and discriminate between self and foreign (non-self) peptides. Of...
Main Authors: | Nguyen, Thanh Binh, Lane, David P., Verma, Chandra Shekhar |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/160817 |
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