Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities
Janus particles are the ones whose surfaces have more than one distinct physical and/or chemical properties, which endow them the ability to self-assemble at interface of dissimilar media. However, existing methods to produce good yields of Janus particles are difficult to scale up. In this work, am...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/161081 |
| _version_ | 1826119292648685568 |
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| author | Tan, Jasmine Si Jia Cao, Xun Huang, Yizhong Chen, Zhong |
| author2 | School of Materials Science and Engineering |
| author_facet | School of Materials Science and Engineering Tan, Jasmine Si Jia Cao, Xun Huang, Yizhong Chen, Zhong |
| author_sort | Tan, Jasmine Si Jia |
| collection | NTU |
| description | Janus particles are the ones whose surfaces have more than one distinct physical and/or chemical properties, which endow them the ability to self-assemble at interface of dissimilar media. However, existing methods to produce good yields of Janus particles are difficult to scale up. In this work, amphiphobic-amphiphilic Janus-like particles are prepared through the ultraviolet irradiation of Pickering emulsions. By assembling at the water/oil interface, pre-functionalized amphiphobic titanium dioxide particles were found to stabilize water-in-oil Pickering emulsions for at least a month. Subjecting emulsion droplets to UV irradiation induces photocatalytic degradation of the coating on exposed particle surfaces. The process is feasible for scaling up to generate larger yields. Even on a lab scale, hundreds of milligrams of Janus-like particles were prepared. The obtained Janus-like particles showed larger affinity for an oil/water interface than their homogeneous counterparts. When employed as encapsulators for the release of molecules in different pH environments, the Janus-like particles provided a slow and controllable release of the cargo throughout a month, opening the possibility for the tailored release of drugs and other molecules. For practical applications, this work demonstrates that high Janus uniformity is not necessary if the particles collectively exhibit an overall Janus behavior. The conceived method is applicable for other particles with photocatalytic properties to create various particle-coating combinations. |
| first_indexed | 2024-10-01T04:57:51Z |
| format | Journal Article |
| id | ntu-10356/161081 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:57:51Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | ntu-10356/1610812022-08-15T02:54:31Z Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities Tan, Jasmine Si Jia Cao, Xun Huang, Yizhong Chen, Zhong School of Materials Science and Engineering Johnson & Johnson Pte. Ltd. Engineering::Materials Janus Particles Pickering Emulsions Janus particles are the ones whose surfaces have more than one distinct physical and/or chemical properties, which endow them the ability to self-assemble at interface of dissimilar media. However, existing methods to produce good yields of Janus particles are difficult to scale up. In this work, amphiphobic-amphiphilic Janus-like particles are prepared through the ultraviolet irradiation of Pickering emulsions. By assembling at the water/oil interface, pre-functionalized amphiphobic titanium dioxide particles were found to stabilize water-in-oil Pickering emulsions for at least a month. Subjecting emulsion droplets to UV irradiation induces photocatalytic degradation of the coating on exposed particle surfaces. The process is feasible for scaling up to generate larger yields. Even on a lab scale, hundreds of milligrams of Janus-like particles were prepared. The obtained Janus-like particles showed larger affinity for an oil/water interface than their homogeneous counterparts. When employed as encapsulators for the release of molecules in different pH environments, the Janus-like particles provided a slow and controllable release of the cargo throughout a month, opening the possibility for the tailored release of drugs and other molecules. For practical applications, this work demonstrates that high Janus uniformity is not necessary if the particles collectively exhibit an overall Janus behavior. The conceived method is applicable for other particles with photocatalytic properties to create various particle-coating combinations. Economic Development Board (EDB) The authors gratefully acknowledge the Economic Development Board of Singapore (S15-1528-IPP) as well as Johnson & Johnson Pte Ltd (project SMART to NTU) for the financial support of this research under the EDB Industrial Postgraduate Programme. 2022-08-15T02:54:31Z 2022-08-15T02:54:31Z 2020 Journal Article Tan, J. S. J., Cao, X., Huang, Y. & Chen, Z. (2020). Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 589, 124460-. https://dx.doi.org/10.1016/j.colsurfa.2020.124460 0927-7757 https://hdl.handle.net/10356/161081 10.1016/j.colsurfa.2020.124460 2-s2.0-85077801869 589 124460 en S15-1528-IPP Colloids and Surfaces A: Physicochemical and Engineering Aspects © 2020 Elsevier B.V. All rights reserved. |
| spellingShingle | Engineering::Materials Janus Particles Pickering Emulsions Tan, Jasmine Si Jia Cao, Xun Huang, Yizhong Chen, Zhong Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities |
| title | Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities |
| title_full | Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities |
| title_fullStr | Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities |
| title_full_unstemmed | Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities |
| title_short | Janus-like particles prepared through partial UV irradiation at the water/oil interface and their encapsulation capabilities |
| title_sort | janus like particles prepared through partial uv irradiation at the water oil interface and their encapsulation capabilities |
| topic | Engineering::Materials Janus Particles Pickering Emulsions |
| url | https://hdl.handle.net/10356/161081 |
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