Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging
Skin plays a significant role in human body function and its collagen states change during the human skin ageing process, which affects skin function. We previously reported on geometry-dependent spectroscopic contrast achieved by spectroscopic micro-optical coherence tomography (SμOCT), which disco...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2022
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| Online Access: | https://hdl.handle.net/10356/161121 |
| _version_ | 1824453690614874112 |
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| author | Ni, Guangming Ge, Xin Liu, Lin Zhang, Jing Wang, Xiangzhou Liu, Juanxiu Liu, Linbo Liu, Yong |
| author2 | School of Electrical and Electronic Engineering |
| author_facet | School of Electrical and Electronic Engineering Ni, Guangming Ge, Xin Liu, Lin Zhang, Jing Wang, Xiangzhou Liu, Juanxiu Liu, Linbo Liu, Yong |
| author_sort | Ni, Guangming |
| collection | NTU |
| description | Skin plays a significant role in human body function and its collagen states change during the human skin ageing process, which affects skin function. We previously reported on geometry-dependent spectroscopic contrast achieved by spectroscopic micro-optical coherence tomography (SμOCT), which discovered that transversely oriented and regularly arranged nano-cylinders selectively backscatter the long-wavelength lights and generate spectral centroid (SC) shifts towards the long wavelengths within a spectral window of 700 - 950 nm. Here we further proposed a novel method towards indicating the state of human skin in vivo using geometry-dependent spectroscopic contrast imaging. The proposed method can obtain spectroscopic contrast images of different human skin layers, including the papillary dermis and reticular dermis, and provide a quantitative method towards indicating collagen state in human skin in vivo. Experimental results have shown that the proposed method may potentially have the ability to assess the state of human skin. |
| first_indexed | 2025-02-19T03:10:26Z |
| format | Journal Article |
| id | ntu-10356/161121 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-02-19T03:10:26Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | ntu-10356/1611212022-08-16T06:17:54Z Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging Ni, Guangming Ge, Xin Liu, Lin Zhang, Jing Wang, Xiangzhou Liu, Juanxiu Liu, Linbo Liu, Yong School of Electrical and Electronic Engineering Engineering::Electrical and electronic engineering Human Skin Collagen Skin plays a significant role in human body function and its collagen states change during the human skin ageing process, which affects skin function. We previously reported on geometry-dependent spectroscopic contrast achieved by spectroscopic micro-optical coherence tomography (SμOCT), which discovered that transversely oriented and regularly arranged nano-cylinders selectively backscatter the long-wavelength lights and generate spectral centroid (SC) shifts towards the long wavelengths within a spectral window of 700 - 950 nm. Here we further proposed a novel method towards indicating the state of human skin in vivo using geometry-dependent spectroscopic contrast imaging. The proposed method can obtain spectroscopic contrast images of different human skin layers, including the papillary dermis and reticular dermis, and provide a quantitative method towards indicating collagen state in human skin in vivo. Experimental results have shown that the proposed method may potentially have the ability to assess the state of human skin. Agency for Science, Technology and Research (A*STAR) Ministry of Education (MOE) Ministry of Health (MOH) This research was supported by the Singapore Ministry of Health’s National Medical Research Council under its Open Fund Individual Research Grant (MOH-OFIRG19may-0009), Ministry of Education Singapore under its Academic Research Fund Tier 1 (2018-T1-001-144), Agency for Science, Technology and Research (A*STAR) under its Industrial Alignment Fund (Pre-positioning) (H17/01/a0/008) and the National Natural Science Foundation of China under Grant 61905036. 2022-08-16T06:17:54Z 2022-08-16T06:17:54Z 2020 Journal Article Ni, G., Ge, X., Liu, L., Zhang, J., Wang, X., Liu, J., Liu, L. & Liu, Y. (2020). Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging. IEEE Photonics Technology Letters, 32(12), 697-700. https://dx.doi.org/10.1109/LPT.2020.2992469 1041-1135 https://hdl.handle.net/10356/161121 10.1109/LPT.2020.2992469 2-s2.0-85085104912 12 32 697 700 en MOH-OFIRG19may-0009 2018-T1-001-144 H17/01/a0/008 IEEE Photonics Technology Letters © 2020 IEEE. All rights reserved. |
| spellingShingle | Engineering::Electrical and electronic engineering Human Skin Collagen Ni, Guangming Ge, Xin Liu, Lin Zhang, Jing Wang, Xiangzhou Liu, Juanxiu Liu, Linbo Liu, Yong Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging |
| title | Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging |
| title_full | Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging |
| title_fullStr | Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging |
| title_full_unstemmed | Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging |
| title_short | Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging |
| title_sort | towards indicating human skin state in vivo using geometry dependent spectroscopic contrast imaging |
| topic | Engineering::Electrical and electronic engineering Human Skin Collagen |
| url | https://hdl.handle.net/10356/161121 |
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