Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides
We show here how the electrochemical reduction signal of graphene oxide nanocolloids is inhibited upon the formation of non-covalent interactions with single stranded DNA oligonucleotides. The drop in the reduction current intensity is strongly influenced by the nucleobase sequence, and can therefor...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2022
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/161866 |
| _version_ | 1826122823962198016 |
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| author | Liang, Yaquan Ang, Wei Li Lim, Rachel Rui Xia Bonanni, Alessandra |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Liang, Yaquan Ang, Wei Li Lim, Rachel Rui Xia Bonanni, Alessandra |
| author_sort | Liang, Yaquan |
| collection | NTU |
| description | We show here how the electrochemical reduction signal of graphene oxide nanocolloids is inhibited upon the formation of non-covalent interactions with single stranded DNA oligonucleotides. The drop in the reduction current intensity is strongly influenced by the nucleobase sequence, and can therefore be directly correlated to the specific DNA homo-oligonucleotide. |
| first_indexed | 2024-10-01T05:54:29Z |
| format | Journal Article |
| id | ntu-10356/161866 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:54:29Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | ntu-10356/1618662022-09-22T05:50:52Z Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides Liang, Yaquan Ang, Wei Li Lim, Rachel Rui Xia Bonanni, Alessandra School of Physical and Mathematical Sciences Science::Chemistry DNA Electrolytic Reduction We show here how the electrochemical reduction signal of graphene oxide nanocolloids is inhibited upon the formation of non-covalent interactions with single stranded DNA oligonucleotides. The drop in the reduction current intensity is strongly influenced by the nucleobase sequence, and can therefore be directly correlated to the specific DNA homo-oligonucleotide. Ministry of Education (MOE) A. B. acknowledges Ministry of Education (MOE) Singapore, Academic Research Fund Tier 1 grant (Reference No. RG88/20) for the financial support. 2022-09-22T05:50:52Z 2022-09-22T05:50:52Z 2022 Journal Article Liang, Y., Ang, W. L., Lim, R. R. X. & Bonanni, A. (2022). Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides. Chemical Communications, 58(16), 2662-2665. https://dx.doi.org/10.1039/d1cc06657a 1359-7345 https://hdl.handle.net/10356/161866 10.1039/d1cc06657a 35107450 2-s2.0-85125020246 16 58 2662 2665 en RG88/20 Chemical Communications © 2022 The Royal Society of Chemistry. All rights reserved. |
| spellingShingle | Science::Chemistry DNA Electrolytic Reduction Liang, Yaquan Ang, Wei Li Lim, Rachel Rui Xia Bonanni, Alessandra Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides |
| title | Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides |
| title_full | Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides |
| title_fullStr | Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides |
| title_full_unstemmed | Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides |
| title_short | Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides |
| title_sort | exploring graphene oxide intrinsic electroactivity to elucidate the non covalent interactions with dna oligonucleotides |
| topic | Science::Chemistry DNA Electrolytic Reduction |
| url | https://hdl.handle.net/10356/161866 |
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