Direct identification of A-to-I editing sites with nanopore native RNA sequencing

Direct identification of A-to-I editing sites with nanopore native RNA sequencing

Inosine is a prevalent RNA modification in animals and is formed when an adenosine is deaminated by the ADAR family of enzymes. Traditionally, inosines are identified indirectly as variants from Illumina RNA-sequencing data because they are interpreted as guanosines by cellular machineries. However,...

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Bibliographic Details
Main Authors: Nguyen, Tram Anh, Heng, Joel Jia Wei, Kaewsapsak, Pornchai, Kok, Louis Eng Piew, Stanojević, Dominik, Liu, Hao, Cardilla, Angelysia, Praditya, Albert, Yi, Zirong, Lin, Mingwan, Aw, Ashley Jong Ghut, Ho, Yin Ying, Peh, Esther Kai Lay, Wang, Yuanming, Zhong, Qixing, Heraud-Farlow, Jacki, Xue, Shifeng, Reversade, Bruno, Walkley, Carl, Ho, Ying Swan, Šikić, Mile, Wan, Yue, Tan, Meng How
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2022
Subjects:
Engineering::Bioengineering
Science::Biological sciences
Gene Expression
RNA Editing
Online Access:https://hdl.handle.net/10356/162250

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