Opportunities and challenges in microbial medium chain fatty acids production from waste biomass

Medium chain fatty acids (MCFAs) that produced from affordable waste biomass via chain elongation (CE) technology are recognized as the potential alternatives to part fossil-derived chemicals, contributing to the sustainable development of economy and environment. The purpose of this review is to pr...

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Main Authors: Wu, Qinglian, Jiang, Yong, Chen, Ying, Liu, Min, Bao, Xian, Guo, Wanqian
Other Authors: School of Civil and Environmental Engineering
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/162371
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author Wu, Qinglian
Jiang, Yong
Chen, Ying
Liu, Min
Bao, Xian
Guo, Wanqian
author2 School of Civil and Environmental Engineering
author_facet School of Civil and Environmental Engineering
Wu, Qinglian
Jiang, Yong
Chen, Ying
Liu, Min
Bao, Xian
Guo, Wanqian
author_sort Wu, Qinglian
collection NTU
description Medium chain fatty acids (MCFAs) that produced from affordable waste biomass via chain elongation (CE) technology are recognized as the potential alternatives to part fossil-derived chemicals, contributing to the sustainable development of economy and environment. The purpose of this review is to provide comprehensive analyses on the opportunities and challenges of MCFAs production and application. First, both two microbial MCFAs synthesis pathways of reverse β-oxidation and fatty acid biosynthesis were introduced/compared in detail to give readers a thorough understanding of the CE process, with the expectation of further boosting MCFAs production by well distinguishing them. Furthermore, the six key MCFAs production bottlenecks, corresponding research progresses, and possible solutions were analyzed. Five major MCFAs production strategies with their production mechanism, performances, and characteristics were also critically assessed. Additionally, the commercial production status was introduced, and future alternative production mode and research priorities were also recommended.
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spelling ntu-10356/1623712022-10-17T04:21:00Z Opportunities and challenges in microbial medium chain fatty acids production from waste biomass Wu, Qinglian Jiang, Yong Chen, Ying Liu, Min Bao, Xian Guo, Wanqian School of Civil and Environmental Engineering Engineering::Civil engineering Chain Elongation Fatty Acid Biosynthesis Medium chain fatty acids (MCFAs) that produced from affordable waste biomass via chain elongation (CE) technology are recognized as the potential alternatives to part fossil-derived chemicals, contributing to the sustainable development of economy and environment. The purpose of this review is to provide comprehensive analyses on the opportunities and challenges of MCFAs production and application. First, both two microbial MCFAs synthesis pathways of reverse β-oxidation and fatty acid biosynthesis were introduced/compared in detail to give readers a thorough understanding of the CE process, with the expectation of further boosting MCFAs production by well distinguishing them. Furthermore, the six key MCFAs production bottlenecks, corresponding research progresses, and possible solutions were analyzed. Five major MCFAs production strategies with their production mechanism, performances, and characteristics were also critically assessed. Additionally, the commercial production status was introduced, and future alternative production mode and research priorities were also recommended. This work was supported by the National Natural Science Foundation of China (52000132 and 51978201). 2022-10-17T04:21:00Z 2022-10-17T04:21:00Z 2021 Journal Article Wu, Q., Jiang, Y., Chen, Y., Liu, M., Bao, X. & Guo, W. (2021). Opportunities and challenges in microbial medium chain fatty acids production from waste biomass. Bioresource Technology, 340, 125633-. https://dx.doi.org/10.1016/j.biortech.2021.125633 0960-8524 https://hdl.handle.net/10356/162371 10.1016/j.biortech.2021.125633 34315125 2-s2.0-85111873641 340 125633 en Bioresource technology © 2021 Elsevier Ltd. All rights reserved.
spellingShingle Engineering::Civil engineering
Chain Elongation
Fatty Acid Biosynthesis
Wu, Qinglian
Jiang, Yong
Chen, Ying
Liu, Min
Bao, Xian
Guo, Wanqian
Opportunities and challenges in microbial medium chain fatty acids production from waste biomass
title Opportunities and challenges in microbial medium chain fatty acids production from waste biomass
title_full Opportunities and challenges in microbial medium chain fatty acids production from waste biomass
title_fullStr Opportunities and challenges in microbial medium chain fatty acids production from waste biomass
title_full_unstemmed Opportunities and challenges in microbial medium chain fatty acids production from waste biomass
title_short Opportunities and challenges in microbial medium chain fatty acids production from waste biomass
title_sort opportunities and challenges in microbial medium chain fatty acids production from waste biomass
topic Engineering::Civil engineering
Chain Elongation
Fatty Acid Biosynthesis
url https://hdl.handle.net/10356/162371
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