Aging patterns of Japanese auditory semantic processing: an fMRI study
The efficacy of listening comprehension is presumably sustained over the life span, contradicting the stereotype of universal cognitive decline. It is thus worth investigating whether and how the preserved auditory semantic function is supported by affected or unaffected neural mechanism with age. T...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2022
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| Online Access: | https://hdl.handle.net/10356/162668 |
| _version_ | 1826122649397362688 |
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| author | Liu, Hengshuang Miyakoshi, Makoto Nakai, Toshiharu Chen, Annabel Shen-Hsing |
| author2 | School of Social Sciences |
| author_facet | School of Social Sciences Liu, Hengshuang Miyakoshi, Makoto Nakai, Toshiharu Chen, Annabel Shen-Hsing |
| author_sort | Liu, Hengshuang |
| collection | NTU |
| description | The efficacy of listening comprehension is presumably sustained over the life span, contradicting the stereotype of universal cognitive decline. It is thus worth investigating whether and how the preserved auditory semantic function is supported by affected or unaffected neural mechanism with age. To investigate this issue, 22 younger and 21 older Japanese adults were imaged in a 3 Tesla MRI scanner while performing an auditory semantic-tone task. Results showed that (a) relative to younger adults, older participants had preserved accuracy and slowed responses, underpinned by weakened interconnectivity and largely unchanged activation and laterality; (b) older adults with superior performance developed increased regional left-lateralization and stronger interregional connectivity within the domain-general networks; (c) these age-related or performance-related cortical reorganizations were largely consistent with neurocognitive aging models that were supported by age-sensitive cognitive domains, suggesting that these models might also be accountable for relatively age-intact cognitive functions such as auditory semantic processing. |
| first_indexed | 2024-10-01T05:51:55Z |
| format | Journal Article |
| id | ntu-10356/162668 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:51:55Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | ntu-10356/1626682022-11-02T07:56:26Z Aging patterns of Japanese auditory semantic processing: an fMRI study Liu, Hengshuang Miyakoshi, Makoto Nakai, Toshiharu Chen, Annabel Shen-Hsing School of Social Sciences Lee Kong Chian School of Medicine (LKCMedicine) Centre for Research and Development in Learning (CRADLE) Social sciences::Psychology Dedifferentiation Compensation The efficacy of listening comprehension is presumably sustained over the life span, contradicting the stereotype of universal cognitive decline. It is thus worth investigating whether and how the preserved auditory semantic function is supported by affected or unaffected neural mechanism with age. To investigate this issue, 22 younger and 21 older Japanese adults were imaged in a 3 Tesla MRI scanner while performing an auditory semantic-tone task. Results showed that (a) relative to younger adults, older participants had preserved accuracy and slowed responses, underpinned by weakened interconnectivity and largely unchanged activation and laterality; (b) older adults with superior performance developed increased regional left-lateralization and stronger interregional connectivity within the domain-general networks; (c) these age-related or performance-related cortical reorganizations were largely consistent with neurocognitive aging models that were supported by age-sensitive cognitive domains, suggesting that these models might also be accountable for relatively age-intact cognitive functions such as auditory semantic processing. Nanyang Technological University This work was supported by the Japan Society for the Promotion of Science (JSPS) under Grants-in-Aid for Scientific Research (KAKENHI #15H03104 and 19H04025); and a funding source for NTU-SUG from Nanyang Technological University. The second author was supported by a generous gift of Swartz Foundation (Old Field, New York). 2022-11-02T07:56:25Z 2022-11-02T07:56:25Z 2022 Journal Article Liu, H., Miyakoshi, M., Nakai, T. & Chen, A. S. (2022). Aging patterns of Japanese auditory semantic processing: an fMRI study. Aging, Neuropsychology and Cognition, 29(2), 213-236. https://dx.doi.org/10.1080/13825585.2020.1861202 1382-5585 https://hdl.handle.net/10356/162668 10.1080/13825585.2020.1861202 33349128 2-s2.0-85097869515 2 29 213 236 en Aging, Neuropsychology and Cognition © 2020 Informa UK Limited, trading as Taylor & Francis Group. All rights reserved. |
| spellingShingle | Social sciences::Psychology Dedifferentiation Compensation Liu, Hengshuang Miyakoshi, Makoto Nakai, Toshiharu Chen, Annabel Shen-Hsing Aging patterns of Japanese auditory semantic processing: an fMRI study |
| title | Aging patterns of Japanese auditory semantic processing: an fMRI study |
| title_full | Aging patterns of Japanese auditory semantic processing: an fMRI study |
| title_fullStr | Aging patterns of Japanese auditory semantic processing: an fMRI study |
| title_full_unstemmed | Aging patterns of Japanese auditory semantic processing: an fMRI study |
| title_short | Aging patterns of Japanese auditory semantic processing: an fMRI study |
| title_sort | aging patterns of japanese auditory semantic processing an fmri study |
| topic | Social sciences::Psychology Dedifferentiation Compensation |
| url | https://hdl.handle.net/10356/162668 |
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