Robust delivery of RIG-I agonists using extracellular vesicles for anti-cancer immunotherapy

Robust delivery of RIG-I agonists using extracellular vesicles for anti-cancer immunotherapy

The RIG-I pathway can be activated by RNA containing 5' triphosphate, leading to type I interferon release and immune activation. Hence, RIG-I agonists have been used to induce immune responses against cancer as potential immunotherapy. However, delivery of 5' triphosphorylated RNA molecul...

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Bibliographic Details
Main Authors: Peng, Boya, Nguyen, Trinh Mai, Jayasinghe, Migara Kavishka, Gao, Chang, Pham, Thach Tuan, Vu, Luyen Tien, Yeo, Eric Yew Meng, Yap, Gracemary, Wang, Lingzhi, Goh, Boon Cher, Tam, Wai Leong, Luo, Dahai, Le, Minh TN
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Medicine
Cancer
Extracellular Vesicles,
Online Access:https://hdl.handle.net/10356/163208

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