Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts

N-heterocyclic carbene (NHC) catalysis has become a versatile catalysis strategy for building molecules via unique reaction modes. Dual catalytic processes using NHCs in combination with additional modulating agents such as another organocatalyst or transition-metal catalyst have also been studied....

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Main Authors: Wang, Hongling, Chi, Robin Yonggui, Huang, Xuan
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/163500
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author Wang, Hongling
Chi, Robin Yonggui
Huang, Xuan
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Wang, Hongling
Chi, Robin Yonggui
Huang, Xuan
author_sort Wang, Hongling
collection NTU
description N-heterocyclic carbene (NHC) catalysis has become a versatile catalysis strategy for building molecules via unique reaction modes. Dual catalytic processes using NHCs in combination with additional modulating agents such as another organocatalyst or transition-metal catalyst have also been studied. The clear selection of cocatalysts has led to enhanced reactivity, increased yields, and/or improved stereoselectivity. This minireview is to provide readers with a brief overview of the development and applications of NHC and hydrogen-bond donor for dual catalytic reactions.
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spelling ntu-10356/1635002022-12-07T08:41:53Z Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts Wang, Hongling Chi, Robin Yonggui Huang, Xuan School of Physical and Mathematical Sciences Science::Chemistry Enantioselective Dual Catalysis N-heterocyclic carbene (NHC) catalysis has become a versatile catalysis strategy for building molecules via unique reaction modes. Dual catalytic processes using NHCs in combination with additional modulating agents such as another organocatalyst or transition-metal catalyst have also been studied. The clear selection of cocatalysts has led to enhanced reactivity, increased yields, and/or improved stereoselectivity. This minireview is to provide readers with a brief overview of the development and applications of NHC and hydrogen-bond donor for dual catalytic reactions. We acknowledge financial support from the National Natural Science Foundation of China (No. 22001173), Basic and Applied Research Foundation of Guangdong (No. 2019A1515110906) and the Project of Department of Education of Guangdong Province (No. 2020KTSCX116), the Shenzhen Science and Technology Foundation (No. KQJSCX20180328100401788) and the Principal Foundation of SZU (No. 8570700000307). 2022-12-07T08:41:53Z 2022-12-07T08:41:53Z 2022 Journal Article Wang, H., Chi, R. Y. & Huang, X. (2022). Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts. European Journal of Organic Chemistry, 2022(27), e202200548-. https://dx.doi.org/10.1002/ejoc.202200548 1434-193X https://hdl.handle.net/10356/163500 10.1002/ejoc.202200548 2-s2.0-85134470132 27 2022 e202200548 en European Journal of Organic Chemistry © 2022 Wiley-VCH GmbH. All rights reserved.
spellingShingle Science::Chemistry
Enantioselective
Dual Catalysis
Wang, Hongling
Chi, Robin Yonggui
Huang, Xuan
Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts
title Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts
title_full Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts
title_fullStr Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts
title_full_unstemmed Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts
title_short Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts
title_sort enantioselective dual catalysis of n heterocyclic carbene and hydrogen bond donor organocatalysts
topic Science::Chemistry
Enantioselective
Dual Catalysis
url https://hdl.handle.net/10356/163500
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AT chirobinyonggui enantioselectivedualcatalysisofnheterocycliccarbeneandhydrogenbonddonororganocatalysts
AT huangxuan enantioselectivedualcatalysisofnheterocycliccarbeneandhydrogenbonddonororganocatalysts