Whole-cell biosynthesis of cytarabine by an unnecessary protein-reduced Escherichia coli that coexpresses purine and uracil phosphorylase

Whole-cell biosynthesis of cytarabine by an unnecessary protein-reduced Escherichia coli that coexpresses purine and uracil phosphorylase

Currently, whole-cell catalysts face challenges due to the complexity of reaction systems, although they have a cost advantage over pure enzymes. In this study, cytarabine was synthesized by purified purine phosphorylase 1 (PNP1) and uracil phosphorylase (UP), and the conversion of cytarabine from a...

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Detalhes bibliográficos
Principais autores: Li, Ping, Jing, Ruxian, Zhou, Mengping, Jia, Pei, Li, Zhuoya, Liu, Guosheng, Wang, Zhenyu, Wang, Hailei
Outros Autores: Nanyang Environment and Water Research Institute
Formato: Journal Article
Idioma:English
Publicado em: 2022
Assuntos:
Science::Biological sciences
Cytarabine
Escherichia Coli
Acesso em linha:https://hdl.handle.net/10356/163555

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