3D bioprinting: materials, processes, and applications

Ageing population and new diseases are requiring the development of novel therapeutical strategies. 3D bioprinting an novel application domain of additive manufacturing emerged as a potential transformative strategy for tissue engineering and regenerative medicine. This paper introduces the concept...

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Main Authors: Bartolo, Paulo, Malshe, Ajay, Ferraris, Eleonora, Koc, Bahattin
Other Authors: School of Mechanical and Aerospace Engineering
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/163559
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author Bartolo, Paulo
Malshe, Ajay
Ferraris, Eleonora
Koc, Bahattin
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Bartolo, Paulo
Malshe, Ajay
Ferraris, Eleonora
Koc, Bahattin
author_sort Bartolo, Paulo
collection NTU
description Ageing population and new diseases are requiring the development of novel therapeutical strategies. 3D bioprinting an novel application domain of additive manufacturing emerged as a potential transformative strategy for tissue engineering and regenerative medicine. This paper introduces the concept of 3D bioprinting, discussing in detail key requirements of bio-inks and main materials used to encapsulate cells. Recent advances related to the use of smart materials and the concept of 4D printing is also discussed. Main 3D bioprinting techniques are described in detail and key limitations highlighted. Successful cases, demonstrating the relevance of 3D bioprinting are also presented. Finally, the paper addresses the main research challenges and future perspectives in the field of 3D bioprinting.
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spelling ntu-10356/1635592022-12-10T23:31:34Z 3D bioprinting: materials, processes, and applications Bartolo, Paulo Malshe, Ajay Ferraris, Eleonora Koc, Bahattin School of Mechanical and Aerospace Engineering Singapore Centre for 3D Printing Engineering::Mechanical engineering Additive Manufacturing Biomedical Ageing population and new diseases are requiring the development of novel therapeutical strategies. 3D bioprinting an novel application domain of additive manufacturing emerged as a potential transformative strategy for tissue engineering and regenerative medicine. This paper introduces the concept of 3D bioprinting, discussing in detail key requirements of bio-inks and main materials used to encapsulate cells. Recent advances related to the use of smart materials and the concept of 4D printing is also discussed. Main 3D bioprinting techniques are described in detail and key limitations highlighted. Successful cases, demonstrating the relevance of 3D bioprinting are also presented. Finally, the paper addresses the main research challenges and future perspectives in the field of 3D bioprinting. Published version 2022-12-09T03:00:32Z 2022-12-09T03:00:32Z 2022 Journal Article Bartolo, P., Malshe, A., Ferraris, E. & Koc, B. (2022). 3D bioprinting: materials, processes, and applications. CIRP Annals - Manufacturing Technology, 71(2), 577-597. https://dx.doi.org/10.1016/j.cirp.2022.06.001 0007-8506 https://hdl.handle.net/10356/163559 10.1016/j.cirp.2022.06.001 2-s2.0-85135401607 2 71 577 597 en CIRP Annals - Manufacturing Technology © 2022 The Author(s). Published by Elsevier Ltd on behalf of CIRP. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/) application/pdf
spellingShingle Engineering::Mechanical engineering
Additive Manufacturing
Biomedical
Bartolo, Paulo
Malshe, Ajay
Ferraris, Eleonora
Koc, Bahattin
3D bioprinting: materials, processes, and applications
title 3D bioprinting: materials, processes, and applications
title_full 3D bioprinting: materials, processes, and applications
title_fullStr 3D bioprinting: materials, processes, and applications
title_full_unstemmed 3D bioprinting: materials, processes, and applications
title_short 3D bioprinting: materials, processes, and applications
title_sort 3d bioprinting materials processes and applications
topic Engineering::Mechanical engineering
Additive Manufacturing
Biomedical
url https://hdl.handle.net/10356/163559
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