The role of tyrosine hydroxylase-dopamine pathway in Parkinson's disease pathogenesis

The role of tyrosine hydroxylase-dopamine pathway in Parkinson's disease pathogenesis

Background: Parkinson’s disease (PD) is characterized by selective and progressive dopamine (DA) neuron loss in the substantia nigra and other brain regions, with the presence of Lewy body formation. Most PD cases are sporadic, whereas monogenic forms of PD have been linked to multiple genes, includ...

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Bibliographic Details
Main Authors: Zhou, Zhi Dong, Saw, Wuan Ting, Ho, Patrick Ghim Hoe, Zhang, Zhi Wei, Zeng, Li, Chang, Ya Yin, Sun, Alfred Xu Yang, Ma, Dong Rui, Wang, Hong Yan, Zhou, Lei, Lim, Kah-Leong, Tan, Eng-King
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Dopamine
Neurodegeneration
Online Access:https://hdl.handle.net/10356/164554

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