MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration

MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration

α-Synuclein (α-syn) is important in synucleinopathies such as Parkinson's disease (PD). While genome-wide association studies (GWASs) of synucleinopathies have identified many risk loci, the underlying genes have not been shown for most loci. Using Drosophila, we screened 3,471 mutant chromosom...

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Bibliographic Details
Main Authors: Ren, Mengda, Yang, Ying, Heng, Kelsey Hwee Yee, Ng, Lu Yi, Chong, Claris Yuin-Yi, Ng, Yan Ting, Gorur-Shandilya, Srinivas, Lee, Rachel Min Qi, Lim, Kah Leong, Zhang, Jing, Koh, Tong-Wey
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Genetic Modifiers
Parkinson's Disease
Online Access:https://hdl.handle.net/10356/164883

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