Expanding the scope of substrate specificity for peptide asparaginyl ligases
Asparaginyl endopeptidases (AEPs) are Asn/Asp (Asx)-specific proteases. Peptide asparaginyl ligases (PALs) belong to AEPs that exhibit dominant ligase activity, making them valuable stand-alone biotechnological and biochemical tools for precision biomanufacturing of proteins. Structure-guided mut...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/165142 |