New miniature chitosan diaphragm-based fabry-perot interferometric sensor for medical applications

Miniature sensors are highly attractive for various applications, especially when space is restricted, such as in invasive blood pressure measurement. Fiber-optic sensors offer excellent solution due to their small size and biocompatibility. In this project, a chitosan diaphragm-based miniature fibe...

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Bibliographic Details
Main Author: Goh, Siew Kee.
Other Authors: Chan Chi Chiu
Format: Final Year Project (FYP)
Language:English
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10356/16519
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author Goh, Siew Kee.
author2 Chan Chi Chiu
author_facet Chan Chi Chiu
Goh, Siew Kee.
author_sort Goh, Siew Kee.
collection NTU
description Miniature sensors are highly attractive for various applications, especially when space is restricted, such as in invasive blood pressure measurement. Fiber-optic sensors offer excellent solution due to their small size and biocompatibility. In this project, a chitosan diaphragm-based miniature fiber-optic Fabry-Perot sensor was developed. Fabrication of this sensor only required simple steps like cleaving, arc fusion splicing and diaphragm formation through surface tension. In addition, it allowed thinner diaphragm to be fabricated and eliminated the hazard of wet etching. Demodulation was carried out to examine air cavity length change of the sensor under pressure change. Low Young’s Modulus of 2283 MPa for unmodified chitosan film allowed the sensor to achieve high pressure sensitivity of 1.35 µm/psi in static pressure measurement in the pressure range of 0 psi to 5 psi. For acoustic pressure measurement, it was capable of detecting real-time response from 20 Hz to 20 kHz with a high sensitivity of -16dB. However, signal-to-noise ratio was unsatisfactory but this could be improved through signal processing in the future. In conclusion, an improved miniature extrinsic Fabry-Perot interferometric sensor was developed in this project. High sensitivity in the low pressure region and wide frequency range makes it a good candidate in biomedical application, such as in real-time invasive blood pressure measurement and in non-invasive blood pressure measurement through the detection of korotkoff sounds.
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spelling ntu-10356/165192023-03-03T15:31:55Z New miniature chitosan diaphragm-based fabry-perot interferometric sensor for medical applications Goh, Siew Kee. Chan Chi Chiu School of Chemical and Biomedical Engineering Network Technology Research Centre DRNTU::Engineering::Chemical engineering::Biochemical engineering Miniature sensors are highly attractive for various applications, especially when space is restricted, such as in invasive blood pressure measurement. Fiber-optic sensors offer excellent solution due to their small size and biocompatibility. In this project, a chitosan diaphragm-based miniature fiber-optic Fabry-Perot sensor was developed. Fabrication of this sensor only required simple steps like cleaving, arc fusion splicing and diaphragm formation through surface tension. In addition, it allowed thinner diaphragm to be fabricated and eliminated the hazard of wet etching. Demodulation was carried out to examine air cavity length change of the sensor under pressure change. Low Young’s Modulus of 2283 MPa for unmodified chitosan film allowed the sensor to achieve high pressure sensitivity of 1.35 µm/psi in static pressure measurement in the pressure range of 0 psi to 5 psi. For acoustic pressure measurement, it was capable of detecting real-time response from 20 Hz to 20 kHz with a high sensitivity of -16dB. However, signal-to-noise ratio was unsatisfactory but this could be improved through signal processing in the future. In conclusion, an improved miniature extrinsic Fabry-Perot interferometric sensor was developed in this project. High sensitivity in the low pressure region and wide frequency range makes it a good candidate in biomedical application, such as in real-time invasive blood pressure measurement and in non-invasive blood pressure measurement through the detection of korotkoff sounds. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2009-05-27T01:28:49Z 2009-05-27T01:28:49Z 2009 2009 Final Year Project (FYP) http://hdl.handle.net/10356/16519 en Nanyang Technological University 72 p. application/pdf
spellingShingle DRNTU::Engineering::Chemical engineering::Biochemical engineering
Goh, Siew Kee.
New miniature chitosan diaphragm-based fabry-perot interferometric sensor for medical applications
title New miniature chitosan diaphragm-based fabry-perot interferometric sensor for medical applications
title_full New miniature chitosan diaphragm-based fabry-perot interferometric sensor for medical applications
title_fullStr New miniature chitosan diaphragm-based fabry-perot interferometric sensor for medical applications
title_full_unstemmed New miniature chitosan diaphragm-based fabry-perot interferometric sensor for medical applications
title_short New miniature chitosan diaphragm-based fabry-perot interferometric sensor for medical applications
title_sort new miniature chitosan diaphragm based fabry perot interferometric sensor for medical applications
topic DRNTU::Engineering::Chemical engineering::Biochemical engineering
url http://hdl.handle.net/10356/16519
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