The cerebellum and anxiety
Although the cerebellum is traditionally known for its role in motor functions, recent evidence points toward the additional involvement of the cerebellum in an array of non-motor functions. One such non-motor function is anxiety behavior: a series of recent studies now implicate the cerebellum in a...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2023
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| Online Access: | https://hdl.handle.net/10356/165613 |
| _version_ | 1826112940014567424 |
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| author | Chin, Pei Wern Augustine, George James |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Chin, Pei Wern Augustine, George James |
| author_sort | Chin, Pei Wern |
| collection | NTU |
| description | Although the cerebellum is traditionally known for its role in motor functions, recent evidence points toward the additional involvement of the cerebellum in an array of non-motor functions. One such non-motor function is anxiety behavior: a series of recent studies now implicate the cerebellum in anxiety. Here, we review evidence regarding the possible role of the cerebellum in anxiety-ranging from clinical studies to experimental manipulation of neural activity-that collectively points toward a role for the cerebellum, and possibly a specific topographical locus within the cerebellum, as one of the orchestrators of anxiety responses. |
| first_indexed | 2024-10-01T03:15:22Z |
| format | Journal Article |
| id | ntu-10356/165613 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:15:22Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | ntu-10356/1656132023-04-09T15:37:35Z The cerebellum and anxiety Chin, Pei Wern Augustine, George James Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Cerebellum Anxiety Although the cerebellum is traditionally known for its role in motor functions, recent evidence points toward the additional involvement of the cerebellum in an array of non-motor functions. One such non-motor function is anxiety behavior: a series of recent studies now implicate the cerebellum in anxiety. Here, we review evidence regarding the possible role of the cerebellum in anxiety-ranging from clinical studies to experimental manipulation of neural activity-that collectively points toward a role for the cerebellum, and possibly a specific topographical locus within the cerebellum, as one of the orchestrators of anxiety responses. Ministry of Education (MOE) Published version This work was supported by the Singapore Ministry of Education under its Singapore Ministry of Education Academic Research Fund Tier 3 (MOE2017-T3-1-002). 2023-04-04T00:46:57Z 2023-04-04T00:46:57Z 2023 Journal Article Chin, P. W. & Augustine, G. J. (2023). The cerebellum and anxiety. Frontiers in Cellular Neuroscience, 17, 1130505-. https://dx.doi.org/10.3389/fncel.2023.1130505 1662-5102 https://hdl.handle.net/10356/165613 10.3389/fncel.2023.1130505 36909285 2-s2.0-85150046448 17 1130505 en MOE2017-T3-1-002 Frontiers in Cellular Neuroscience © 2023 Chin and Augustine. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. application/pdf |
| spellingShingle | Science::Medicine Cerebellum Anxiety Chin, Pei Wern Augustine, George James The cerebellum and anxiety |
| title | The cerebellum and anxiety |
| title_full | The cerebellum and anxiety |
| title_fullStr | The cerebellum and anxiety |
| title_full_unstemmed | The cerebellum and anxiety |
| title_short | The cerebellum and anxiety |
| title_sort | cerebellum and anxiety |
| topic | Science::Medicine Cerebellum Anxiety |
| url | https://hdl.handle.net/10356/165613 |
| work_keys_str_mv | AT chinpeiwern thecerebellumandanxiety AT augustinegeorgejames thecerebellumandanxiety AT chinpeiwern cerebellumandanxiety AT augustinegeorgejames cerebellumandanxiety |