Development of optofluidics chip
Fiber optical biosensors have a huge potential for simple, continuous, rapid in-situ monitoring of biomolecules in biomedical, environmental, and food industries. In particular, photonic crystal fibers are promising because liquid or gaseous sample materials can be introduced into the air holes with...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/10356/16581 |
| _version_ | 1811695746380988416 |
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| author | Cham, Qinghui |
| author2 | Chan Chi Chiu |
| author_facet | Chan Chi Chiu Cham, Qinghui |
| author_sort | Cham, Qinghui |
| collection | NTU |
| description | Fiber optical biosensors have a huge potential for simple, continuous, rapid in-situ monitoring of biomolecules in biomedical, environmental, and food industries. In particular, photonic crystal fibers are promising because liquid or gaseous sample materials can be introduced into the air holes within the fiber, where it can interact directly with the guided light. As such, a higher interaction can be achieved and the robustness of the fiber is not compromised.
In this project, a biosensing layer is immobilized in the holes within a hollow-core
photonic crystal fiber. This biosensing layer then selectively binds to glucose molecules and alters the refractive index of the surface which in turn modifies the transmission of a light through the fiber.
Numerical methods and experiments involving a hollow-core photonic crystal fiber were
performed in an attempt to establish a relationship between change in refractive index and position of band gap edges. |
| first_indexed | 2024-10-01T07:28:22Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/16581 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:28:22Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | ntu-10356/165812023-03-03T15:39:11Z Development of optofluidics chip Cham, Qinghui Chan Chi Chiu School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering::Biotechnology Fiber optical biosensors have a huge potential for simple, continuous, rapid in-situ monitoring of biomolecules in biomedical, environmental, and food industries. In particular, photonic crystal fibers are promising because liquid or gaseous sample materials can be introduced into the air holes within the fiber, where it can interact directly with the guided light. As such, a higher interaction can be achieved and the robustness of the fiber is not compromised. In this project, a biosensing layer is immobilized in the holes within a hollow-core photonic crystal fiber. This biosensing layer then selectively binds to glucose molecules and alters the refractive index of the surface which in turn modifies the transmission of a light through the fiber. Numerical methods and experiments involving a hollow-core photonic crystal fiber were performed in an attempt to establish a relationship between change in refractive index and position of band gap edges. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2009-05-27T04:28:35Z 2009-05-27T04:28:35Z 2009 2009 Final Year Project (FYP) http://hdl.handle.net/10356/16581 en Nanyang Technological University 73 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Chemical engineering::Biotechnology Cham, Qinghui Development of optofluidics chip |
| title | Development of optofluidics chip |
| title_full | Development of optofluidics chip |
| title_fullStr | Development of optofluidics chip |
| title_full_unstemmed | Development of optofluidics chip |
| title_short | Development of optofluidics chip |
| title_sort | development of optofluidics chip |
| topic | DRNTU::Engineering::Chemical engineering::Biotechnology |
| url | http://hdl.handle.net/10356/16581 |
| work_keys_str_mv | AT chamqinghui developmentofoptofluidicschip |