Collagen nanofibrous scaffolds for tissue engineering

The goal of this project is to research the properties and fabrication process of gelatin and collagen scaffolds. The scaffolds were produced by electrospinning, which is a process that can formulate nanofibers by electrically charging a suspended droplet of polymer melt or solution [1]. The scaffol...

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Main Author: Piak, Xiang Fu.
Other Authors: Chew Sing Yian
Format: Final Year Project (FYP)
Language:English
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10356/16626
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author Piak, Xiang Fu.
author2 Chew Sing Yian
author_facet Chew Sing Yian
Piak, Xiang Fu.
author_sort Piak, Xiang Fu.
collection NTU
description The goal of this project is to research the properties and fabrication process of gelatin and collagen scaffolds. The scaffolds were produced by electrospinning, which is a process that can formulate nanofibers by electrically charging a suspended droplet of polymer melt or solution [1]. The scaffolds were then chemically crosslinked, after which their mechanical properties were tested in their wet states. Different parameters were also used to electrospin the scaffolds, which investigated the effects of varying the concentration of the polymer (gelatin, collagen) and varying the amount of solvent (acetic acid, 2,2,2-trifluoroethanol) used. Two general types of scaffold were investigated in this project. The first type is scaffolds which have nanofibers that are aligned to one another and can be useful for cultivating nerve cells. The other scaffolds are specimens that have nanofibers that are randomly orientated.
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spelling ntu-10356/166262023-03-03T15:35:16Z Collagen nanofibrous scaffolds for tissue engineering Piak, Xiang Fu. Chew Sing Yian School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering::Biotechnology The goal of this project is to research the properties and fabrication process of gelatin and collagen scaffolds. The scaffolds were produced by electrospinning, which is a process that can formulate nanofibers by electrically charging a suspended droplet of polymer melt or solution [1]. The scaffolds were then chemically crosslinked, after which their mechanical properties were tested in their wet states. Different parameters were also used to electrospin the scaffolds, which investigated the effects of varying the concentration of the polymer (gelatin, collagen) and varying the amount of solvent (acetic acid, 2,2,2-trifluoroethanol) used. Two general types of scaffold were investigated in this project. The first type is scaffolds which have nanofibers that are aligned to one another and can be useful for cultivating nerve cells. The other scaffolds are specimens that have nanofibers that are randomly orientated. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2009-05-27T07:31:24Z 2009-05-27T07:31:24Z 2009 2009 Final Year Project (FYP) http://hdl.handle.net/10356/16626 en Nanyang Technological University 56 p. application/pdf
spellingShingle DRNTU::Engineering::Chemical engineering::Biotechnology
Piak, Xiang Fu.
Collagen nanofibrous scaffolds for tissue engineering
title Collagen nanofibrous scaffolds for tissue engineering
title_full Collagen nanofibrous scaffolds for tissue engineering
title_fullStr Collagen nanofibrous scaffolds for tissue engineering
title_full_unstemmed Collagen nanofibrous scaffolds for tissue engineering
title_short Collagen nanofibrous scaffolds for tissue engineering
title_sort collagen nanofibrous scaffolds for tissue engineering
topic DRNTU::Engineering::Chemical engineering::Biotechnology
url http://hdl.handle.net/10356/16626
work_keys_str_mv AT piakxiangfu collagennanofibrousscaffoldsfortissueengineering