Protein aggregation and stress response in yeast defective for the ubiquitin-proteasome system
Cdc48 is an ATPase chaperone for ER ubiquitinated protein translocation. Cim3 is a 19S regulatory ATPase subunit that unfolds polyubiquitylated substrates to feed them into the proteasomal catalytic core. The dynamic control of protein homeostasis via ubiquitin-proteasome system (UPS) is crucial to...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/166464 |