Developing a zebrafish model of bisphosphonate induced osteonecrosis of jaw to define cellular and molecular mechanisms
Bisphosphonates are critical drugs of the orthopaedic clinic, which act by inhibiting osteoclast resorptive activity and thus promote bone density. They are commonly used for treating Osteogenesis Imperfecta (OI), Paget’s disease, osteoporosis, and bone metastasis. In particular, the global rise in...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
| Published: |
Nanyang Technological University
2023
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/168636 |