On biosafety of Sn-containing halide perovskites
Lead based halide perovskites have made great progress in various fields especially optoelectronic devices, but the health risk caused by heavy metal lead strongly blocks their widespread applications. Therefore, Pb free perovskites such as Sn based halide perovskites have been proposed and are expe...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2023
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/169337 |
| _version_ | 1811681132819775488 |
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| author | Xiao, Lian An, Tingting Deng, Chuxia Xu, Xiaoling Sun, Handong |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Xiao, Lian An, Tingting Deng, Chuxia Xu, Xiaoling Sun, Handong |
| author_sort | Xiao, Lian |
| collection | NTU |
| description | Lead based halide perovskites have made great progress in various fields especially optoelectronic devices, but the health risk caused by heavy metal lead strongly blocks their widespread applications. Therefore, Pb free perovskites such as Sn based halide perovskites have been proposed and are expected to address the toxicity issue. However, until now, the toxicity and environmental impact of tin-based halide perovskites are still debated. This even raised a critical question about whether it is still worth deploying tin-containing halide perovskites which needs to be answered urgently but has so far remained elusive. In this work, we carefully analyse the practical application conditions of tin-based halide perovskites e.g., solar cells and conduct a comprehensive toxicity evaluation under these realistic situations. Our results including the organ weight index, blood analysis, immunohistochemistry (IHC) tests and next generation sequencing (RNA sequencing) demonstrated that even in the worst condition of large-scale applications of Sn based halide perovskites, neither obvious acute toxicity nor risk at a gene level can be observed. Thus, we conclude that Sn based halide perovskites are bio safe and substituting lead with tin in halide perovskites is applicable. |
| first_indexed | 2024-10-01T03:36:05Z |
| format | Journal Article |
| id | ntu-10356/169337 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:36:05Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | ntu-10356/1693372023-07-17T15:34:52Z On biosafety of Sn-containing halide perovskites Xiao, Lian An, Tingting Deng, Chuxia Xu, Xiaoling Sun, Handong School of Physical and Mathematical Sciences Science::Physics Heavy Metals Lead Compounds Lead based halide perovskites have made great progress in various fields especially optoelectronic devices, but the health risk caused by heavy metal lead strongly blocks their widespread applications. Therefore, Pb free perovskites such as Sn based halide perovskites have been proposed and are expected to address the toxicity issue. However, until now, the toxicity and environmental impact of tin-based halide perovskites are still debated. This even raised a critical question about whether it is still worth deploying tin-containing halide perovskites which needs to be answered urgently but has so far remained elusive. In this work, we carefully analyse the practical application conditions of tin-based halide perovskites e.g., solar cells and conduct a comprehensive toxicity evaluation under these realistic situations. Our results including the organ weight index, blood analysis, immunohistochemistry (IHC) tests and next generation sequencing (RNA sequencing) demonstrated that even in the worst condition of large-scale applications of Sn based halide perovskites, neither obvious acute toxicity nor risk at a gene level can be observed. Thus, we conclude that Sn based halide perovskites are bio safe and substituting lead with tin in halide perovskites is applicable. Agency for Science, Technology and Research (A*STAR) Submitted/Accepted version This work was supported by A*STAR under project AME-IRGA20E5c0083, The Science and Technology Development Fund (FDCT) grants (0065/2022/A2, 0097/2021/A2, 0045/2021/AFJ, and 0092/2020/AMJ) of Macau SAR, China, and the Natural Science Foundation of China (NSFC): 82030094. 2023-07-13T05:24:55Z 2023-07-13T05:24:55Z 2023 Journal Article Xiao, L., An, T., Deng, C., Xu, X. & Sun, H. (2023). On biosafety of Sn-containing halide perovskites. Energy & Environmental Science, 16(5), 2120-2132. https://dx.doi.org/10.1039/d2ee02510h 1754-5692 https://hdl.handle.net/10356/169337 10.1039/d2ee02510h 2-s2.0-85152093298 5 16 2120 2132 en AME-IRG-A20E5c0083 Energy & Environmental Science © 2023 The Royal Society of Chemistry. All rights reserved. This paper was published in Energy & Environmental Science and is made available with permission of The Royal Society of Chemistry. application/pdf |
| spellingShingle | Science::Physics Heavy Metals Lead Compounds Xiao, Lian An, Tingting Deng, Chuxia Xu, Xiaoling Sun, Handong On biosafety of Sn-containing halide perovskites |
| title | On biosafety of Sn-containing halide perovskites |
| title_full | On biosafety of Sn-containing halide perovskites |
| title_fullStr | On biosafety of Sn-containing halide perovskites |
| title_full_unstemmed | On biosafety of Sn-containing halide perovskites |
| title_short | On biosafety of Sn-containing halide perovskites |
| title_sort | on biosafety of sn containing halide perovskites |
| topic | Science::Physics Heavy Metals Lead Compounds |
| url | https://hdl.handle.net/10356/169337 |
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