Membrane potential-dependent uptake of cationic oligoimidazolium mediates bacterial DNA damage and death

Membrane potential-dependent uptake of cationic oligoimidazolium mediates bacterial DNA damage and death

The treatment of bacterial infections is becoming increasingly challenging with the emergence of antimicrobial resistance. Thus, the development of antimicrobials with novel mechanisms of action is much needed. Previously, we designed several cationic main-chain imidazolium compounds and identified...

Full description

Bibliographic Details
Main Authors: Yong, Melvin, Kok, Zhi Y., Koh, Chong Hui, Zhong, Wenbin, Ng, Justin T. Y., Mu, Yuguang, Chan-Park, Mary B., Gan, Yunn-Hwen
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Biological sciences
Engineering::Bioengineering
DNA Damage
Cationic
Online Access:https://hdl.handle.net/10356/169440

Internet

https://hdl.handle.net/10356/169440

Similar Items