A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine

A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine

Coronavirus disease-19 (Covid-19) pandemic have demonstrated the importantance of vaccines in disease prevention. Self-amplifying mRNA vaccines could be another option for disease prevention if demonstrated to be safe and immunogenic. Phase 1 of this randomized, double-blinded, placebo-controlled tr...

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Bibliographic Details
Main Authors: Low, Jenny G., de Alwis, Ruklanthi, Chen, Shiwei, Kalimuddin, Shirin, Leong, Yan Shan, Mah, Tania Ken Lin, Yuen, Natalene, Tan, Hwee Cheng, Zhang, Summer L., Sim, Jean X. Y., Chan, Yvonne F. Z., Syenina, Ayesa, Yee, Jia Xin, Ong, Eugenia Z., Sekulovich, Rose, Sullivan, Brian B., Lindert, Kelly, Sullivan, Sean M., Chivukula, Pad, Hughes, Steven G., Ooi, Eng Eong
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Biological sciences
SARS-CoV-2 Vaccine
Neutralizing Antibody
Online Access:https://hdl.handle.net/10356/169469

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