High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules
The inappropriate usage of biochemical molecules has led to serious environmental problems, and there is an urgent need to seek low-cost biochemical molecular sensors. Surface-enhanced Raman scattering (SERS) has received extensive attention due to their high sensitivity and specificity but is limit...
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Format: | Journal Article |
Language: | English |
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2023
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Online Access: | https://hdl.handle.net/10356/170165 |
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author | Wang, Yifan Chen, Zhiming Zeng, Pan Cao, An Zhang, Tao Li, Yue |
author2 | School of Physical and Mathematical Sciences |
author_facet | School of Physical and Mathematical Sciences Wang, Yifan Chen, Zhiming Zeng, Pan Cao, An Zhang, Tao Li, Yue |
author_sort | Wang, Yifan |
collection | NTU |
description | The inappropriate usage of biochemical molecules has led to serious environmental problems, and there is an urgent need to seek low-cost biochemical molecular sensors. Surface-enhanced Raman scattering (SERS) has received extensive attention due to their high sensitivity and specificity but is limited by low utilization and high cost. Here, we develop a high-throughput and highly sensitive NIR-SERS biochemical sensor (HNIR-SERS sensor) by combining inkjet printing technology with plasmonic metallic nanoparticles. First, we fabricated gridded substrates using imprinting technology, where the separated areas are in a typical cubic arrangement. Porous Au@AuAg yolk-shell nanorods (NRs), serving as assembly units, were then regularly assembled on the substrates by inkjet printing, forming an HNIR-SERS sensor. This new kind of HNIR-SERS sensor can achieve high sensitivity detection of multi biochemical molecules in one sensor substrate. As an example, this HNIR-SERS sensor enables efficient detection of 4-aminothiophenol (4-ATP) and rhodamine 6G (R6G), with an enhancement factor (EF) of 108 for 4-ATP. This work provides an effective method to achieve high-throughput and low-cost NIR-SERS sensors for pushing the practical application in Raman detection chips. |
first_indexed | 2024-10-01T04:25:56Z |
format | Journal Article |
id | ntu-10356/170165 |
institution | Nanyang Technological University |
language | English |
last_indexed | 2024-10-01T04:25:56Z |
publishDate | 2023 |
record_format | dspace |
spelling | ntu-10356/1701652023-08-30T03:16:15Z High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules Wang, Yifan Chen, Zhiming Zeng, Pan Cao, An Zhang, Tao Li, Yue School of Physical and Mathematical Sciences Science::Physics Biochemical Molecules Enhanced Raman Scattering The inappropriate usage of biochemical molecules has led to serious environmental problems, and there is an urgent need to seek low-cost biochemical molecular sensors. Surface-enhanced Raman scattering (SERS) has received extensive attention due to their high sensitivity and specificity but is limited by low utilization and high cost. Here, we develop a high-throughput and highly sensitive NIR-SERS biochemical sensor (HNIR-SERS sensor) by combining inkjet printing technology with plasmonic metallic nanoparticles. First, we fabricated gridded substrates using imprinting technology, where the separated areas are in a typical cubic arrangement. Porous Au@AuAg yolk-shell nanorods (NRs), serving as assembly units, were then regularly assembled on the substrates by inkjet printing, forming an HNIR-SERS sensor. This new kind of HNIR-SERS sensor can achieve high sensitivity detection of multi biochemical molecules in one sensor substrate. As an example, this HNIR-SERS sensor enables efficient detection of 4-aminothiophenol (4-ATP) and rhodamine 6G (R6G), with an enhancement factor (EF) of 108 for 4-ATP. This work provides an effective method to achieve high-throughput and low-cost NIR-SERS sensors for pushing the practical application in Raman detection chips. The authors acknowledge financial support from the National Science Fund for Distinguished Young Scholars (Grant No. 51825103), the Natural Science Foundation of China (Grant No. 92263209, 52001306), and the HFIPS Director’s Fund (Grant No. YZJJZX202019). The Scientific Instrument Developing Project of the Chinese Academy of Sciences (Grant No. E14BBGU52G1). 2023-08-30T03:16:15Z 2023-08-30T03:16:15Z 2023 Journal Article Wang, Y., Chen, Z., Zeng, P., Cao, A., Zhang, T. & Li, Y. (2023). High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules. Journal of Materials Chemistry C, 11(13), 4486-4491. https://dx.doi.org/10.1039/d2tc05542b 2050-7526 https://hdl.handle.net/10356/170165 10.1039/d2tc05542b 2-s2.0-85151072059 13 11 4486 4491 en Journal of Materials Chemistry C © 2023 The Royal Society of Chemistry. All rights reserved. |
spellingShingle | Science::Physics Biochemical Molecules Enhanced Raman Scattering Wang, Yifan Chen, Zhiming Zeng, Pan Cao, An Zhang, Tao Li, Yue High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules |
title | High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules |
title_full | High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules |
title_fullStr | High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules |
title_full_unstemmed | High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules |
title_short | High-throughput surface-enhanced Raman scattering sensors for near-infrared detection of biochemical molecules |
title_sort | high throughput surface enhanced raman scattering sensors for near infrared detection of biochemical molecules |
topic | Science::Physics Biochemical Molecules Enhanced Raman Scattering |
url | https://hdl.handle.net/10356/170165 |
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