Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

Adenosine-to-inosine RNA editing, which is catalyzed by adenosine deaminases acting on RNA (ADAR) family of enzymes, ADAR1 and ADAR2, has been shown to contribute to multiple cancers. However, other than the chronic myeloid leukemia blast crisis, relatively little is known about its role in other ty...

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Bibliographic Details
Main Authors: Guo, Mingrui, Chan, Tim Hon Man, Zhou, Qiling, An, Omer, Li, Ying, Song, Yangyang, Tan, Zi Hui, Ng, Vanessa Hui En, Peramangalam, Philomina Sona, Tan, Zhi Qing, Cao, Xinang, Iwanaga, Eisaku, Matsuoka, Masao, Ooi, Melissa G. M., Jen, Wei Ying, Koh, Liang Piu, Chan, Esther, Tan, Lip Kun, Goh, Yufen, Wang, Wilson, Koh, Bryan T. H., Chun, Chan Ming, Fullwood, Melissa Jane, Chng, Wee Joo, Osato, Motomi, Pulikkan, John Anto, Yang, Henry, Chen, Leilei, Tenen, Daniel G.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Science::Biological sciences
Acute Myeloid Leukemia
Core Binding Factor
Online Access:https://hdl.handle.net/10356/170596

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