Pillar[n]arene-based polymeric systems for biomedical applications
The study of biomedical applications based on supramolecular chemistry from versatile fascinating macrocyclic molecules to various self-assembled architectures has achieved considerable headway in the past decades. Herein, recent advances on pillar[n]arene-based polymers involving the synthesis, sel...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2023
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/170652 |
| _version_ | 1811689578687365120 |
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| author | Zhou, Le Cao, Shuai Liu, Chang Zhang, Huacheng Zhao, Yanli |
| author2 | School of Chemistry, Chemical Engineering and Biotechnology |
| author_facet | School of Chemistry, Chemical Engineering and Biotechnology Zhou, Le Cao, Shuai Liu, Chang Zhang, Huacheng Zhao, Yanli |
| author_sort | Zhou, Le |
| collection | NTU |
| description | The study of biomedical applications based on supramolecular chemistry from versatile fascinating macrocyclic molecules to various self-assembled architectures has achieved considerable headway in the past decades. Herein, recent advances on pillar[n]arene-based polymers involving the synthesis, self-assembly as well as their practical and promising applications in controlled drug release, chemotherapy, photodynamic therapy, and anti-bacteria are holistically summarized. Through direct and powerful covalent and supplementary non-covalent strategies, functional pillar[n]arene-based polymers combining intelligent and controllable characteristics could be thoroughly constructed, offering marvelous prospects for promoting biomedical materials. In particular, pillar[n]arenes serving as terminal groups, side chains, cross-linkers, and building blocks are integrated into polymeric architectures to endow the entire supramolecular systems with more intriguing properties, such as distinct self-assembly behavior and charming stimuli-responsiveness. Some integral characterization tools are also employed to facilitate a deep understanding of the analytical process and interesting results. Overall, this review could lay a sound basis for the development of supramolecular system-based biomedical applications. |
| first_indexed | 2024-10-01T05:50:20Z |
| format | Journal Article |
| id | ntu-10356/170652 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:50:20Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | ntu-10356/1706522023-09-25T04:29:33Z Pillar[n]arene-based polymeric systems for biomedical applications Zhou, Le Cao, Shuai Liu, Chang Zhang, Huacheng Zhao, Yanli School of Chemistry, Chemical Engineering and Biotechnology Engineering::Bioengineering Biomedicine Pillar[n]arenes The study of biomedical applications based on supramolecular chemistry from versatile fascinating macrocyclic molecules to various self-assembled architectures has achieved considerable headway in the past decades. Herein, recent advances on pillar[n]arene-based polymers involving the synthesis, self-assembly as well as their practical and promising applications in controlled drug release, chemotherapy, photodynamic therapy, and anti-bacteria are holistically summarized. Through direct and powerful covalent and supplementary non-covalent strategies, functional pillar[n]arene-based polymers combining intelligent and controllable characteristics could be thoroughly constructed, offering marvelous prospects for promoting biomedical materials. In particular, pillar[n]arenes serving as terminal groups, side chains, cross-linkers, and building blocks are integrated into polymeric architectures to endow the entire supramolecular systems with more intriguing properties, such as distinct self-assembly behavior and charming stimuli-responsiveness. Some integral characterization tools are also employed to facilitate a deep understanding of the analytical process and interesting results. Overall, this review could lay a sound basis for the development of supramolecular system-based biomedical applications. National Research Foundation (NRF) H.Z. acknowledges the financial support from the “Young Talent Support Plan” (No. 050700-71240000000046) of Xi’an Jiaotong University and Natural Science Foundation of Shaanxi Province (No. 2021JM-006). This research is also supported by the National Research Foundation Singapore under Its Competitive Research Programme (No. NRF-CRP26-2021-0002). 2023-09-25T04:29:33Z 2023-09-25T04:29:33Z 2023 Journal Article Zhou, L., Cao, S., Liu, C., Zhang, H. & Zhao, Y. (2023). Pillar[n]arene-based polymeric systems for biomedical applications. Coordination Chemistry Reviews, 491, 215260-. https://dx.doi.org/10.1016/j.ccr.2023.215260 0010-8545 https://hdl.handle.net/10356/170652 10.1016/j.ccr.2023.215260 2-s2.0-85161262921 491 215260 en NRF-CRP26-2021-0002 Coordination Chemistry Reviews © 2023 Elsevier B.V. All rights reserved. |
| spellingShingle | Engineering::Bioengineering Biomedicine Pillar[n]arenes Zhou, Le Cao, Shuai Liu, Chang Zhang, Huacheng Zhao, Yanli Pillar[n]arene-based polymeric systems for biomedical applications |
| title | Pillar[n]arene-based polymeric systems for biomedical applications |
| title_full | Pillar[n]arene-based polymeric systems for biomedical applications |
| title_fullStr | Pillar[n]arene-based polymeric systems for biomedical applications |
| title_full_unstemmed | Pillar[n]arene-based polymeric systems for biomedical applications |
| title_short | Pillar[n]arene-based polymeric systems for biomedical applications |
| title_sort | pillar n arene based polymeric systems for biomedical applications |
| topic | Engineering::Bioengineering Biomedicine Pillar[n]arenes |
| url | https://hdl.handle.net/10356/170652 |
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