A 52-year-old woman with beading of intracranial arteries
A 52-year-old woman of Indian ethnicity with a history of well-controlled hypertension, hyperlipidaemia and recurrent transient ischaemic attacks presented with altered mentation and slurred speech. Physical examination revealed generalised weakness. Initial blood tests showed raised total whit...
| Main Authors: | , , , , |
|---|---|
| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2023
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/170981 |
| _version_ | 1811689233952276480 |
|---|---|
| author | Tan, Guan Zhong Yu, Wai Yung Chng, Soke Miang Lee, Hwei Yee Lin, Xuling |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Tan, Guan Zhong Yu, Wai Yung Chng, Soke Miang Lee, Hwei Yee Lin, Xuling |
| author_sort | Tan, Guan Zhong |
| collection | NTU |
| description | A 52-year-old woman of Indian ethnicity with a history
of well-controlled hypertension, hyperlipidaemia and
recurrent transient ischaemic attacks presented with
altered mentation and slurred speech. Physical examination
revealed generalised weakness. Initial blood tests
showed raised total white cell count, raised erythrocyte
sedimentation rate at 35mm/h and fasting low-density
lipoprotein of 1.7mmol/L. Magnetic resonance imaging
(MRI) of the brain showed small acute infarcts scattered
in bilateral deep white matter (Fig. 1A), with extensive
periventricular, deep and subcortical white matter
leukoariosis (Fig. 1B) indicative of advanced small
vessel disease. Angiography showed stenosis along the
right anterior cerebral artery and beading of the left
posterior cerebral artery (Fig. 1C). Digital subtraction
angiography (DSA) showed beading along the right
posterior cerebral artery (Fig. 1D). |
| first_indexed | 2024-10-01T05:44:51Z |
| format | Journal Article |
| id | ntu-10356/170981 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:44:51Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | ntu-10356/1709812023-10-15T15:38:24Z A 52-year-old woman with beading of intracranial arteries Tan, Guan Zhong Yu, Wai Yung Chng, Soke Miang Lee, Hwei Yee Lin, Xuling Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Central-nervous-system Primary Angiitis A 52-year-old woman of Indian ethnicity with a history of well-controlled hypertension, hyperlipidaemia and recurrent transient ischaemic attacks presented with altered mentation and slurred speech. Physical examination revealed generalised weakness. Initial blood tests showed raised total white cell count, raised erythrocyte sedimentation rate at 35mm/h and fasting low-density lipoprotein of 1.7mmol/L. Magnetic resonance imaging (MRI) of the brain showed small acute infarcts scattered in bilateral deep white matter (Fig. 1A), with extensive periventricular, deep and subcortical white matter leukoariosis (Fig. 1B) indicative of advanced small vessel disease. Angiography showed stenosis along the right anterior cerebral artery and beading of the left posterior cerebral artery (Fig. 1C). Digital subtraction angiography (DSA) showed beading along the right posterior cerebral artery (Fig. 1D). Published version 2023-10-10T01:25:21Z 2023-10-10T01:25:21Z 2022 Journal Article Tan, G. Z., Yu, W. Y., Chng, S. M., Lee, H. Y. & Lin, X. (2022). A 52-year-old woman with beading of intracranial arteries. Annals of the Academy of Medicine, Singapore, 51(4), 255-258. https://dx.doi.org/10.47102/annals-acadmedsg.2021314 0304-4602 https://hdl.handle.net/10356/170981 10.47102/annals-acadmedsg.2021314 35506413 4 51 255 258 en Annals of the Academy of Medicine, Singapore © 2022 The Author(s). This is an open-access article distributed under the terms of the Creative Commons License. application/pdf |
| spellingShingle | Science::Medicine Central-nervous-system Primary Angiitis Tan, Guan Zhong Yu, Wai Yung Chng, Soke Miang Lee, Hwei Yee Lin, Xuling A 52-year-old woman with beading of intracranial arteries |
| title | A 52-year-old woman with beading of intracranial arteries |
| title_full | A 52-year-old woman with beading of intracranial arteries |
| title_fullStr | A 52-year-old woman with beading of intracranial arteries |
| title_full_unstemmed | A 52-year-old woman with beading of intracranial arteries |
| title_short | A 52-year-old woman with beading of intracranial arteries |
| title_sort | 52 year old woman with beading of intracranial arteries |
| topic | Science::Medicine Central-nervous-system Primary Angiitis |
| url | https://hdl.handle.net/10356/170981 |
| work_keys_str_mv | AT tanguanzhong a52yearoldwomanwithbeadingofintracranialarteries AT yuwaiyung a52yearoldwomanwithbeadingofintracranialarteries AT chngsokemiang a52yearoldwomanwithbeadingofintracranialarteries AT leehweiyee a52yearoldwomanwithbeadingofintracranialarteries AT linxuling a52yearoldwomanwithbeadingofintracranialarteries AT tanguanzhong 52yearoldwomanwithbeadingofintracranialarteries AT yuwaiyung 52yearoldwomanwithbeadingofintracranialarteries AT chngsokemiang 52yearoldwomanwithbeadingofintracranialarteries AT leehweiyee 52yearoldwomanwithbeadingofintracranialarteries AT linxuling 52yearoldwomanwithbeadingofintracranialarteries |