The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer

The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer

AXL is a receptor tyrosine kinase that is often overexpressed in cancers. It contributes to pathophysiology in cancer progression and therapeutic resistance, making it an emerging therapeutic target. The first-in-class AXL inhibitor bemcentinib (R428/BGB324) has been granted fast track designation b...

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Bibliographic Details
Main Authors: Yeo, Xun Hui, Sundararajan, Vignesh, Wu, Zhengwei, Phua, Cheryl Zi Jin, Ho, Yin Ying, Peh, Esther Kai Lay, Chiu, Yi-Chia, Tan, Tuan Zea, Kappei, Dennis, Ho, Ying Swan, Tan, David Shao Peng, Tam, Wai Leong, Huang, Ruby Yun-Ju
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Biological sciences
Ovary Tumor
AXL Receptor Tyrosine Kinase
Online Access:https://hdl.handle.net/10356/171552

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