Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells
Fluorescent, CdSe/CdS core/crown heterostructured nanoplatelets (NPLs) were transferred to the water via a simple, single-step ligand exchange using 2-mercaptopropionic acid in a simple extraction process. These stable, aqueous NPLs were loaded with a modal drug, 5-aminolevulinic acid (ALA). ALA-loa...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2023
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/172114 |
| _version_ | 1811692171277893632 |
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| author | Onbasli, Kubra Demirci, Gozde Isik, Furkan Durmusoglu, Emek Goksu Demir, Hilmi Volkan Acar, Havva Yagci |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Onbasli, Kubra Demirci, Gozde Isik, Furkan Durmusoglu, Emek Goksu Demir, Hilmi Volkan Acar, Havva Yagci |
| author_sort | Onbasli, Kubra |
| collection | NTU |
| description | Fluorescent, CdSe/CdS core/crown heterostructured nanoplatelets (NPLs) were transferred to the water via a simple, single-step ligand exchange using 2-mercaptopropionic acid in a simple extraction process. These stable, aqueous NPLs were loaded with a modal drug, 5-aminolevulinic acid (ALA). ALA-loaded NPLs emerged as a new class of theranostic nanoparticles for image-guided enhanced photodynamic therapy of both androgen-dependent and -independent human prostate cancer cells. |
| first_indexed | 2024-10-01T06:31:32Z |
| format | Journal Article |
| id | ntu-10356/172114 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:31:32Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | ntu-10356/1721142023-11-24T02:17:18Z Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells Onbasli, Kubra Demirci, Gozde Isik, Furkan Durmusoglu, Emek Goksu Demir, Hilmi Volkan Acar, Havva Yagci School of Physical and Mathematical Sciences School of Electrical and Electronic Engineering School of Materials Science and Engineering LUMINOUS! Centre of Excellence for Semiconductor Lighting & Displays The Photonics Institute Science::Chemistry Nanoplatelet Cancer Cells Fluorescent, CdSe/CdS core/crown heterostructured nanoplatelets (NPLs) were transferred to the water via a simple, single-step ligand exchange using 2-mercaptopropionic acid in a simple extraction process. These stable, aqueous NPLs were loaded with a modal drug, 5-aminolevulinic acid (ALA). ALA-loaded NPLs emerged as a new class of theranostic nanoparticles for image-guided enhanced photodynamic therapy of both androgen-dependent and -independent human prostate cancer cells. KO thanks Koc University Seed Fund for the financial support. HVD also acknowledges the support from TU¨BA. 2023-11-24T02:17:18Z 2023-11-24T02:17:18Z 2023 Journal Article Onbasli, K., Demirci, G., Isik, F., Durmusoglu, E. G., Demir, H. V. & Acar, H. Y. (2023). Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells. Chemical Communications, 59(70), 10512-10515. https://dx.doi.org/10.1039/D3CC02929H 1359-7345 https://hdl.handle.net/10356/172114 10.1039/D3CC02929H 70 59 10512 10515 en Chemical Communications © 2023 The Royal Society of Chemistry. All rights reserved. |
| spellingShingle | Science::Chemistry Nanoplatelet Cancer Cells Onbasli, Kubra Demirci, Gozde Isik, Furkan Durmusoglu, Emek Goksu Demir, Hilmi Volkan Acar, Havva Yagci Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells |
| title | Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells |
| title_full | Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells |
| title_fullStr | Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells |
| title_full_unstemmed | Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells |
| title_short | Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells |
| title_sort | aqueous colloidal nanoplatelets for imaging and improved ala based photodynamic therapy of prostate cancer cells |
| topic | Science::Chemistry Nanoplatelet Cancer Cells |
| url | https://hdl.handle.net/10356/172114 |
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