APOE4 carrier status determines association between white matter disease and grey matter atrophy in early-stage dementia

APOE4 carrier status determines association between white matter disease and grey matter atrophy in early-stage dementia

White matter hyperintensities, a neuroimaging marker of small-vessel cerebrovascular disease and apolipoprotein ε4 (APOE4) allele, are important dementia risk factors. However, APOE4 as a key effect modifier in the relationship between white matter hyperintensities and grey matter volume needs furth...

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Bibliographic Details
Main Authors: Vipin, Ashwati, Kumar, Dilip, Soo, See Ann, Zailan, Fatin Zahra, Leow, Yi Jin, Koh, Chen Ling, Ng, Adeline Su Lyn, Ng, Kok Pin, Kandiah, Nagaendran
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Medicine
White Matter Hyperintensity
Dementia
Online Access:https://hdl.handle.net/10356/172169

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