Transcriptional regulation of oil biosynthesis in plants
With the steeply rising demand for vegetable oil as part of the human diet and a source of sustainable biofuel, clear understanding of the mechanisms of plant oil biosynthesis becomes imminent for strategizing efficient vegetable oil production. Transcription factor (TF) interactions describe a k...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/172475 |
| _version_ | 1811690939967602688 |
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| author | Yang, Yuzhou |
| author2 | Ma Wei |
| author_facet | Ma Wei Yang, Yuzhou |
| author_sort | Yang, Yuzhou |
| collection | NTU |
| description | With the steeply rising demand for vegetable oil as part of the human diet and a source of
sustainable biofuel, clear understanding of the mechanisms of plant oil biosynthesis becomes
imminent for strategizing efficient vegetable oil production. Transcription factor (TF) interactions
describe a key regulatory mechanism through which plant development and metabolism is
regulated. In this work, bZIP52 was characterized as an interacting partner of the Arabidopsis
WRINKLED1 (AtWRI1), a pivotal regulator of plant oil biosynthesis, thereby reducing AtWRI1-
mediated lipid biosynthesis. Further data revealed a mechanism of bZIP52 repressing AtWRI1’s
transcriptional activity. In a separate study, we identified a MYB transcription factor as a novel transcriptional
regulator of FATTY ACID ELONGASE 1 (FAE1), with a negative regulatory effect on plant lipid
biosynthesis, and ability to modulate fatty acid composition in seeds. Together, both studies
reveal previously uncharacterized regulatory mechanisms and provide insights on seed oil
biosynthesis for potential metabolic engineering approaches. |
| first_indexed | 2024-10-01T06:11:58Z |
| format | Thesis-Doctor of Philosophy |
| id | ntu-10356/172475 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:11:58Z |
| publishDate | 2023 |
| publisher | Nanyang Technological University |
| record_format | dspace |
| spelling | ntu-10356/1724752024-01-04T06:32:51Z Transcriptional regulation of oil biosynthesis in plants Yang, Yuzhou Ma Wei School of Biological Sciences weima@ntu.edu.sg Science::Biological sciences With the steeply rising demand for vegetable oil as part of the human diet and a source of sustainable biofuel, clear understanding of the mechanisms of plant oil biosynthesis becomes imminent for strategizing efficient vegetable oil production. Transcription factor (TF) interactions describe a key regulatory mechanism through which plant development and metabolism is regulated. In this work, bZIP52 was characterized as an interacting partner of the Arabidopsis WRINKLED1 (AtWRI1), a pivotal regulator of plant oil biosynthesis, thereby reducing AtWRI1- mediated lipid biosynthesis. Further data revealed a mechanism of bZIP52 repressing AtWRI1’s transcriptional activity. In a separate study, we identified a MYB transcription factor as a novel transcriptional regulator of FATTY ACID ELONGASE 1 (FAE1), with a negative regulatory effect on plant lipid biosynthesis, and ability to modulate fatty acid composition in seeds. Together, both studies reveal previously uncharacterized regulatory mechanisms and provide insights on seed oil biosynthesis for potential metabolic engineering approaches. Doctor of Philosophy 2023-12-11T11:43:23Z 2023-12-11T11:43:23Z 2023 Thesis-Doctor of Philosophy Yang, Y. (2023). Transcriptional regulation of oil biosynthesis in plants. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/172475 https://hdl.handle.net/10356/172475 10.32657/10356/172475 en This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). application/pdf Nanyang Technological University |
| spellingShingle | Science::Biological sciences Yang, Yuzhou Transcriptional regulation of oil biosynthesis in plants |
| title | Transcriptional regulation of oil biosynthesis in plants |
| title_full | Transcriptional regulation of oil biosynthesis in plants |
| title_fullStr | Transcriptional regulation of oil biosynthesis in plants |
| title_full_unstemmed | Transcriptional regulation of oil biosynthesis in plants |
| title_short | Transcriptional regulation of oil biosynthesis in plants |
| title_sort | transcriptional regulation of oil biosynthesis in plants |
| topic | Science::Biological sciences |
| url | https://hdl.handle.net/10356/172475 |
| work_keys_str_mv | AT yangyuzhou transcriptionalregulationofoilbiosynthesisinplants |