Dose response assessment of silica exposure and poisoning of construction workers

Airborne exposure to silica, below statutory industrial standards, can cause silica exposure and poisoning in construction workers at higher rates than predicted. This research aimed to assess the respiratory health of construction workers exposed to silica from tiles, bricks, mortar, and concrete....

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Main Authors: Xiao, Peng, Li, Yuanzhe
Other Authors: School of Materials Science and Engineering
Format: Journal Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/173740
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author Xiao, Peng
Li, Yuanzhe
author2 School of Materials Science and Engineering
author_facet School of Materials Science and Engineering
Xiao, Peng
Li, Yuanzhe
author_sort Xiao, Peng
collection NTU
description Airborne exposure to silica, below statutory industrial standards, can cause silica exposure and poisoning in construction workers at higher rates than predicted. This research aimed to assess the respiratory health of construction workers exposed to silica from tiles, bricks, mortar, and concrete. The study found a positive correlation between construction material dust and fume exposures and workplace seniority. Silica poisoning was dose-dependent on cumulative silica dust or fumes exposure. The average industrial silica particles and emissions BMDLs were 0.68 and 0.30 mg year/m3, respectively. Silica dust and fume BMDLs for silica poisoning were 0.02 mg/m3 and 0.01 mg/m3, respectively. The study concluded that the current exposure levels for silica in China should be re-evaluated, and operational cumulative exposure limits should be established for better prevention of silica poisoning. The study also noted that disparities in sensitivity to silica poisoning may be related to genetic factors and gene-environment interactions.
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spelling ntu-10356/1737402024-03-01T15:46:29Z Dose response assessment of silica exposure and poisoning of construction workers Xiao, Peng Li, Yuanzhe School of Materials Science and Engineering Medicine, Health and Life Sciences Construction workers Silica exposure Airborne exposure to silica, below statutory industrial standards, can cause silica exposure and poisoning in construction workers at higher rates than predicted. This research aimed to assess the respiratory health of construction workers exposed to silica from tiles, bricks, mortar, and concrete. The study found a positive correlation between construction material dust and fume exposures and workplace seniority. Silica poisoning was dose-dependent on cumulative silica dust or fumes exposure. The average industrial silica particles and emissions BMDLs were 0.68 and 0.30 mg year/m3, respectively. Silica dust and fume BMDLs for silica poisoning were 0.02 mg/m3 and 0.01 mg/m3, respectively. The study concluded that the current exposure levels for silica in China should be re-evaluated, and operational cumulative exposure limits should be established for better prevention of silica poisoning. The study also noted that disparities in sensitivity to silica poisoning may be related to genetic factors and gene-environment interactions. Published version This research was funded by Enerstay Sustainability Pte Ltd (Singapore) Grant Call (Call 1/2022) _SUST (Project ID CAA-2003), Singapore. 2024-02-26T05:25:43Z 2024-02-26T05:25:43Z 2023 Journal Article Xiao, P. & Li, Y. (2023). Dose response assessment of silica exposure and poisoning of construction workers. Environmental Pollutants and Bioavailability, 35(1). https://dx.doi.org/10.1080/26395940.2023.2190489 2639-5940 https://hdl.handle.net/10356/173740 10.1080/26395940.2023.2190489 2-s2.0-85150350510 1 35 en CAA-2003 Environmental Pollutants and Bioavailability © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent. application/pdf
spellingShingle Medicine, Health and Life Sciences
Construction workers
Silica exposure
Xiao, Peng
Li, Yuanzhe
Dose response assessment of silica exposure and poisoning of construction workers
title Dose response assessment of silica exposure and poisoning of construction workers
title_full Dose response assessment of silica exposure and poisoning of construction workers
title_fullStr Dose response assessment of silica exposure and poisoning of construction workers
title_full_unstemmed Dose response assessment of silica exposure and poisoning of construction workers
title_short Dose response assessment of silica exposure and poisoning of construction workers
title_sort dose response assessment of silica exposure and poisoning of construction workers
topic Medicine, Health and Life Sciences
Construction workers
Silica exposure
url https://hdl.handle.net/10356/173740
work_keys_str_mv AT xiaopeng doseresponseassessmentofsilicaexposureandpoisoningofconstructionworkers
AT liyuanzhe doseresponseassessmentofsilicaexposureandpoisoningofconstructionworkers