Dynamic altruistic cooperation within breast tumors
Social behaviors such as altruism, where one self-sacrifices for collective benefits, critically influence an organism's survival and responses to the environment. Such behaviors are widely exemplified in nature but have been underexplored in cancer cells which are conventionally seen as selfis...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2024
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/173761 |
| _version_ | 1824453482058350592 |
|---|---|
| author | Muhammad Sufyan Bin Masroni Lee, Kee Wah Lee, Victor Kwan Min Ng, Siok Bian Law, Chao Teng Poon, Kok Siong Lee, Bernett Teck Kwong Liu, Zhehao Tan, Yuen Peng Chng, Wee Ling Tucker, Steven Ngo, Lynette Su-Mien Yip, George Wai Cheong Nga, Min En Hue, Susan Swee Shan Putti, Thomas Choudary Bay, Boon Huat Lin, Qingsong Zhou, Lihan Hartman, Mikael Loh, Tze Ping Lakshmanan, Manikandan Lee, Sook Yee Tergaonkar, Vinay Chua, Huiwen Lee, Adeline Voon Hui Yeo, Eric Yew Meng Li, Mo-Huang Chang, Chan Fong Kee, Zizheng Tan, Karen Mei-Ling Tan, Soo Yong Koay, Evelyn Siew-Chuan Archetti, Marco Leong, Sai Mun |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Muhammad Sufyan Bin Masroni Lee, Kee Wah Lee, Victor Kwan Min Ng, Siok Bian Law, Chao Teng Poon, Kok Siong Lee, Bernett Teck Kwong Liu, Zhehao Tan, Yuen Peng Chng, Wee Ling Tucker, Steven Ngo, Lynette Su-Mien Yip, George Wai Cheong Nga, Min En Hue, Susan Swee Shan Putti, Thomas Choudary Bay, Boon Huat Lin, Qingsong Zhou, Lihan Hartman, Mikael Loh, Tze Ping Lakshmanan, Manikandan Lee, Sook Yee Tergaonkar, Vinay Chua, Huiwen Lee, Adeline Voon Hui Yeo, Eric Yew Meng Li, Mo-Huang Chang, Chan Fong Kee, Zizheng Tan, Karen Mei-Ling Tan, Soo Yong Koay, Evelyn Siew-Chuan Archetti, Marco Leong, Sai Mun |
| author_sort | Muhammad Sufyan Bin Masroni |
| collection | NTU |
| description | Social behaviors such as altruism, where one self-sacrifices for collective benefits, critically influence an organism's survival and responses to the environment. Such behaviors are widely exemplified in nature but have been underexplored in cancer cells which are conventionally seen as selfish competitive players. This multidisciplinary study explores altruism and its mechanism in breast cancer cells and its contribution to chemoresistance. |
| first_indexed | 2025-02-19T03:07:07Z |
| format | Journal Article |
| id | ntu-10356/173761 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-02-19T03:07:07Z |
| publishDate | 2024 |
| record_format | dspace |
| spelling | ntu-10356/1737612024-03-03T15:38:41Z Dynamic altruistic cooperation within breast tumors Muhammad Sufyan Bin Masroni Lee, Kee Wah Lee, Victor Kwan Min Ng, Siok Bian Law, Chao Teng Poon, Kok Siong Lee, Bernett Teck Kwong Liu, Zhehao Tan, Yuen Peng Chng, Wee Ling Tucker, Steven Ngo, Lynette Su-Mien Yip, George Wai Cheong Nga, Min En Hue, Susan Swee Shan Putti, Thomas Choudary Bay, Boon Huat Lin, Qingsong Zhou, Lihan Hartman, Mikael Loh, Tze Ping Lakshmanan, Manikandan Lee, Sook Yee Tergaonkar, Vinay Chua, Huiwen Lee, Adeline Voon Hui Yeo, Eric Yew Meng Li, Mo-Huang Chang, Chan Fong Kee, Zizheng Tan, Karen Mei-Ling Tan, Soo Yong Koay, Evelyn Siew-Chuan Archetti, Marco Leong, Sai Mun Lee Kong Chian School of Medicine (LKCMedicine) Medicine, Health and Life Sciences Altruism Breast neoplasms Social behaviors such as altruism, where one self-sacrifices for collective benefits, critically influence an organism's survival and responses to the environment. Such behaviors are widely exemplified in nature but have been underexplored in cancer cells which are conventionally seen as selfish competitive players. This multidisciplinary study explores altruism and its mechanism in breast cancer cells and its contribution to chemoresistance. Agency for Science, Technology and Research (A*STAR) Ministry of Education (MOE) National Medical Research Council (NMRC) Published version This work was supported by funds from the Singapore Cancer Society (to ESCK), Agency for Science, Technology and Research (A*STAR)(A*STAR-SERC Public Service Fund 1121202021 to ESCK, A*STAR-EPTL COT Fund EPTL/10S10COT-0019 to ESCK and A*STAR-DxD GAP Fund to ESCK), National University Health System (NUHS Bridging fund to ESCK, NUHS Internal Funding/MOE AcRF Tier 1 T1-NUHS O-CRG 2016 Oct-20 to ESCK), National Medical Research Council (NMRC–NIG NMRC/CNIG/1119/2014 to KMLT), Ministry of Education (MOE T1 & NUHS O-CRG (T1- NUHS Joint Grant Call FY17 - 2nd call-10) to VKML), Startup Grants from the Department of Pathology, National University of Singapore (to SML and KSP) and the National University of Singapore (NUS Postgraduate Research Scholarships and NUSMed Postdoctoral Fellowships to MSBM and KWL). 2024-02-26T08:03:46Z 2024-02-26T08:03:46Z 2023 Journal Article Muhammad Sufyan Bin Masroni, Lee, K. W., Lee, V. K. M., Ng, S. B., Law, C. T., Poon, K. S., Lee, B. T. K., Liu, Z., Tan, Y. P., Chng, W. L., Tucker, S., Ngo, L. S., Yip, G. W. C., Nga, M. E., Hue, S. S. S., Putti, T. C., Bay, B. H., Lin, Q., Zhou, L., ...Leong, S. M. (2023). Dynamic altruistic cooperation within breast tumors. Molecular Cancer, 22(1), 206-. https://dx.doi.org/10.1186/s12943-023-01896-7 1476-4598 https://hdl.handle.net/10356/173761 10.1186/s12943-023-01896-7 38093346 2-s2.0-85179662877 1 22 206 en Molecular Cancer © 2023 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. application/pdf |
| spellingShingle | Medicine, Health and Life Sciences Altruism Breast neoplasms Muhammad Sufyan Bin Masroni Lee, Kee Wah Lee, Victor Kwan Min Ng, Siok Bian Law, Chao Teng Poon, Kok Siong Lee, Bernett Teck Kwong Liu, Zhehao Tan, Yuen Peng Chng, Wee Ling Tucker, Steven Ngo, Lynette Su-Mien Yip, George Wai Cheong Nga, Min En Hue, Susan Swee Shan Putti, Thomas Choudary Bay, Boon Huat Lin, Qingsong Zhou, Lihan Hartman, Mikael Loh, Tze Ping Lakshmanan, Manikandan Lee, Sook Yee Tergaonkar, Vinay Chua, Huiwen Lee, Adeline Voon Hui Yeo, Eric Yew Meng Li, Mo-Huang Chang, Chan Fong Kee, Zizheng Tan, Karen Mei-Ling Tan, Soo Yong Koay, Evelyn Siew-Chuan Archetti, Marco Leong, Sai Mun Dynamic altruistic cooperation within breast tumors |
| title | Dynamic altruistic cooperation within breast tumors |
| title_full | Dynamic altruistic cooperation within breast tumors |
| title_fullStr | Dynamic altruistic cooperation within breast tumors |
| title_full_unstemmed | Dynamic altruistic cooperation within breast tumors |
| title_short | Dynamic altruistic cooperation within breast tumors |
| title_sort | dynamic altruistic cooperation within breast tumors |
| topic | Medicine, Health and Life Sciences Altruism Breast neoplasms |
| url | https://hdl.handle.net/10356/173761 |
| work_keys_str_mv | AT muhammadsufyanbinmasroni dynamicaltruisticcooperationwithinbreasttumors AT leekeewah dynamicaltruisticcooperationwithinbreasttumors AT leevictorkwanmin dynamicaltruisticcooperationwithinbreasttumors AT ngsiokbian dynamicaltruisticcooperationwithinbreasttumors AT lawchaoteng dynamicaltruisticcooperationwithinbreasttumors AT poonkoksiong dynamicaltruisticcooperationwithinbreasttumors AT leebernettteckkwong dynamicaltruisticcooperationwithinbreasttumors AT liuzhehao dynamicaltruisticcooperationwithinbreasttumors AT tanyuenpeng dynamicaltruisticcooperationwithinbreasttumors AT chngweeling dynamicaltruisticcooperationwithinbreasttumors AT tuckersteven dynamicaltruisticcooperationwithinbreasttumors AT ngolynettesumien dynamicaltruisticcooperationwithinbreasttumors AT yipgeorgewaicheong dynamicaltruisticcooperationwithinbreasttumors AT ngaminen dynamicaltruisticcooperationwithinbreasttumors AT huesusansweeshan dynamicaltruisticcooperationwithinbreasttumors AT puttithomaschoudary dynamicaltruisticcooperationwithinbreasttumors AT bayboonhuat dynamicaltruisticcooperationwithinbreasttumors AT linqingsong dynamicaltruisticcooperationwithinbreasttumors AT zhoulihan dynamicaltruisticcooperationwithinbreasttumors AT hartmanmikael dynamicaltruisticcooperationwithinbreasttumors AT lohtzeping dynamicaltruisticcooperationwithinbreasttumors AT lakshmananmanikandan dynamicaltruisticcooperationwithinbreasttumors AT leesookyee dynamicaltruisticcooperationwithinbreasttumors AT tergaonkarvinay dynamicaltruisticcooperationwithinbreasttumors AT chuahuiwen dynamicaltruisticcooperationwithinbreasttumors AT leeadelinevoonhui dynamicaltruisticcooperationwithinbreasttumors AT yeoericyewmeng dynamicaltruisticcooperationwithinbreasttumors AT limohuang dynamicaltruisticcooperationwithinbreasttumors AT changchanfong dynamicaltruisticcooperationwithinbreasttumors AT keezizheng dynamicaltruisticcooperationwithinbreasttumors AT tankarenmeiling dynamicaltruisticcooperationwithinbreasttumors AT tansooyong dynamicaltruisticcooperationwithinbreasttumors AT koayevelynsiewchuan dynamicaltruisticcooperationwithinbreasttumors AT archettimarco dynamicaltruisticcooperationwithinbreasttumors AT leongsaimun dynamicaltruisticcooperationwithinbreasttumors |