Alterations to DNA methylation patterns induced by chemotherapy treatment are associated with negative impacts on the olfactory pathway

Alterations to DNA methylation patterns induced by chemotherapy treatment are associated with negative impacts on the olfactory pathway

Background: Exposure to cytotoxic chemotherapy treatment may alter DNA methylation (DNAm) in breast cancer patients. Methods: We performed DNAm analysis in 125 breast cancer patients with blood drawn before and after chemotherapy, using the Illumina MethylationEPIC array. DNAm changes of 588,798 ind...

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Bibliographic Details
Main Authors: Ho, Peh Joo, Khng, Alexis Jiaying, Tan, Benita Kiat-Tee, Lim, Geok Hoon, Tan, Su-Ming, Tan, Veronique Kiak Mien, Tan, Ryan Shea Ying Cong, Lim, Elaine Hsuen, Iau, Philip Tsau-Choong, Chew, Ying Jia, Lim, Yi Ying, Hartman, Mikael, Tan, Ern Yu, Li, Jingmei
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Epigenetic modifcation
Breast cancer
Online Access:https://hdl.handle.net/10356/173869

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