A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria

A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria

The rise of MDR Gram-negative bacteria (GNB), especially those resistant to last-resort drugs such as carbapenems and colistin, is a global health risk and calls for increased efforts to discover new antimicrobial compounds. We previously reported that polyimidazolium (PIM) compounds exhibited signi...

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Bibliographic Details
Main Authors: Chen, Yahua, Yong, Melvin, Li, Ming, Si, Zhangyong, Koh, Chong Hui, Lau, Pearlyn, Chang, Yi Wei, Teo, Jeanette, Chan-Park, Mary B., Gan, Yunn-Hwen
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2024
Subjects:
Chemistry
Antibiotic agent
Drug resistance
Online Access:https://hdl.handle.net/10356/174218

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